5-BROMO-2-METHOXY-3-CYANOPYRIDINE

Base Information

Chemical Name:5-BROMO-2-METHOXY-3-CYANOPYRIDINE
CAS No.:884495-39-0
Molecular Formula:C6H7BrN2O
Molecular Weight:203.038
Hs Code.:2933399090
Mol file:884495-39-0.mol

Synonyms:3-Amino-5-bromo-2-methoxypyridine;5-Bromo-2-(methyloxy)-3-pyridinamine;

Suppliers and Price of 5-BROMO-2-METHOXY-3-CYANOPYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-2-methoxypyridin-3-amine
50mg
$ 60.00

SynQuest Laboratories
3-Amino-5-bromo-2-methoxypyridine
25 g
$ 250.00

SynQuest Laboratories
3-Amino-5-bromo-2-methoxypyridine
1 g
$ 45.00

SynQuest Laboratories
3-Amino-5-bromo-2-methoxypyridine
5 g
$ 75.00

Sigma-Aldrich
5-Bromo-2-methoxypyridin-3-amine Aldrich
1g
$ 388.00

Medical Isotopes, Inc.
5-Bromo-2-methoxypyridin-3-amine 96%
5 g
$ 519.00

Matrix Scientific
5-Bromo-2-methoxy-3-pyridinamine 95+%
5g
$ 34.00

Matrix Scientific
5-Bromo-2-methoxy-3-pyridinamine 95+%
1g
$ 10.00

Frontier Specialty Chemicals
3-Amino-5-bromo-2-methoxypyridine 98%
5g
$ 15.00

Frontier Specialty Chemicals
3-Amino-5-bromo-2-methoxypyridine 98%
1g
$ 5.00

Total 73 raw suppliers

Chemical Property of 5-BROMO-2-METHOXY-3-CYANOPYRIDINE

Chemical Property:

Vapor Pressure:0.00296mmHg at 25°C
Melting Point:53-55℃
Refractive Index:1.602
Boiling Point:284.5 °C at 760 mmHg
PKA:1.98±0.20(Predicted)
Flash Point:125.9 °C
PSA：48.14000
Density:1.622 g/cm³
LogP:2.01610
Storage Temp.:Room temperature.
Water Solubility.:Slightly soluble in water.

Purity/Quality:

98%, ^*data from raw suppliers

5-Bromo-2-methoxypyridin-3-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-37/38-41-43
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-Amino-5-bromo-2-methoxypyridine is used as pharmaceutical intermediate.

Technology Process of 5-BROMO-2-METHOXY-3-CYANOPYRIDINE

There total 1 articles about 5-BROMO-2-METHOXY-3-CYANOPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67443-38-3
5-bromo-2-chloro-3-nitropyridine

: 884495-39-0
5-bromo-2-(methyloxy)-3-pyridinamine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 0 - 20 °C

2: tin(II) chloride dihdyrate / ethyl acetate / 4 h / Reflux

With tin(II) chloride dihdyrate; In methanol; ethyl acetate;
DOI:10.1016/j.bmcl.2011.12.136

Reference yield: 96.0%

: 884495-39-0
5-bromo-2-(methyloxy)-3-pyridinamine

: 23095-31-0
3,4-dimethoxybenzene-1-sulfonyl chloride

: 1366131-15-8
N-[5-bromo-2-(methyloxy)-3-pyridinyl]-3,4-bis(methyloxy)benzenesulfonamide

Guidance literature:: With dmap; In pyridine; at 20 ℃; for 0.166667h;

Reference yield: 95.0%

: 884495-39-0
5-bromo-2-(methyloxy)-3-pyridinamine

: 73183-34-3
bis(pinacol)diborane

: 893440-50-1
2-(methyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinamine

Guidance literature:: With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; at 20 - 100 ℃;