Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate

Base Information

Chemical Name:Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate
CAS No.:873673-51-9
Molecular Formula:C13H13 N3 O3
Molecular Weight:259.265
Hs Code.:
DSSTox Substance ID:DTXSID60700953
Wikidata:Q82632479

Synonyms:873673-51-9;DTXSID60700953;FT-0720651;Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate

Suppliers and Price of Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:259.09569129
Heavy Atom Count:19
Complexity:436

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CN1C(=NC=C(C1=O)N)C2=CC=CC=C2

Technology Process of Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate

There total 5 articles about Methyl (5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (5-Benzyloxycarbonylamino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetic acid methyl ester

: 873673-51-9
(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetic acid methyl ester

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 20 ℃; for 2h;
DOI:10.1016/S0968-0896(01)00007-4

Reference yield:

: 148747-59-5
5-benzyloxycarbonylamino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-ylmethylcarboxylic acid

: 873673-51-9
(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.83 g / diethyl ether; methanol / 0 °C

2: 95 percent / hydrogen; HCl / Pd-C / ethyl acetate; methanol / 2 h / 20 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; diethyl ether; ethyl acetate;
DOI:10.1016/S0968-0896(01)00007-4

Reference yield:

: 331985-92-3
N-(tert-butoxycarbonylmethyl)benzamidine hydrochloride

: 873673-51-9
(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / water; toluene

2: toluene; acetonitrile / 17 h / 80 °C

3: methanol

With sodium carbonate; In methanol; water; toluene; acetonitrile;
DOI:10.3987/COM-12-12432