{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Base Information

Chemical Name:{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate
CAS No.:1369768-86-4
Molecular Formula:C₁₅H₁₉FO₅
Molecular Weight:298.311
Hs Code.:

Synonyms:{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Suppliers and Price of {(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

There total 6 articles about {(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-05-4,9003-20-7
vinyl acetate

: 1369768-85-3
(1S,2R)-1-[3-fluoro-4-(methoxymethoxy)phenyl]cyclopropane-1,2-dimethanol

: 1369768-86-4
{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Guidance literature:: Lipase acrylic resin from Candida Antarctica; In tetrahydrofuran; at 10 - 35 ℃; for 15h; Enzymatic reaction;

Reference yield:

: 1369768-84-2
(1S,5R)-1-[3-fluoro-4-(methoxymethoxy)phenyl]-3-oxabicyclo[3.1.0]hexan-2-one

: 1369768-86-4
{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium borohydride / tetrahydrofuran; methanol / 15 h / -30 - 35 °C

2: Lipase acrylic resin from Candida Antarctica / tetrahydrofuran / 15 h / 10 - 35 °C / Enzymatic reaction

With lithium borohydride; Lipase acrylic resin from Candida Antarctica; In tetrahydrofuran; methanol;

Reference yield:

: 1369768-83-1
2-[3-fluoro-4-(methoxymethoxy)phenyl]acetonitrile

: 1369768-86-4
{(1R,2S)-2-[3-fluoro-4-(methoxymethoxy)phenyl]-2-(hydroxymethyl)cyclopropyl}methyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -15 °C

1.2: -15 - 35 °C

2.1: lithium borohydride / tetrahydrofuran; methanol / 15 h / -30 - 35 °C

3.1: Lipase acrylic resin from Candida Antarctica / tetrahydrofuran / 15 h / 10 - 35 °C / Enzymatic reaction

With lithium borohydride; sodium hexamethyldisilazane; Lipase acrylic resin from Candida Antarctica; In tetrahydrofuran; methanol;