methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Base Information

Chemical Name:methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate
CAS No.:78443-78-4
Molecular Formula:C₂₁H₂₂Cl₂O₅
Molecular Weight:425.309
Hs Code.:

Synonyms:methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Suppliers and Price of methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

There total 5 articles about methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

: 78443-77-3
methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-5-hydroxy-3-oxo-6-heptenoate

: 78443-78-4
methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 0.25h;
DOI:10.1021/jm00152a001

Reference yield:

: 100-39-0
benzyl bromide

: 78443-78-4
methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) K₂CO₃ / 1.) DMF, 60 deg C, 30 min, 2.) DMF, 60 deg C, 1 h

2: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 1 h, 2.) hexane, THF, -78 deg C, 1 h

3: 1.) NaH, 2.) n-BuLi

4: 99.5 percent / NaBH₄ / ethanol / 0.25 h

With sodium tetrahydroborate; n-butyllithium; sodium hydride; potassium carbonate; In ethanol;
DOI:10.1021/jm00152a001

Reference yield:

: 78443-72-8
4,6-dichlorosalicylaldehyde

: 78443-78-4
methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) K₂CO₃ / 1.) DMF, 60 deg C, 30 min, 2.) DMF, 60 deg C, 1 h

2: 1.) n-BuLi / 1.) hexane, THF, -78 deg C, 1 h, 2.) hexane, THF, -78 deg C, 1 h

3: 1.) NaH, 2.) n-BuLi

4: 99.5 percent / NaBH₄ / ethanol / 0.25 h

With sodium tetrahydroborate; n-butyllithium; sodium hydride; potassium carbonate; In ethanol;
DOI:10.1021/jm00152a001