78443-72-8

Usage

Uses

Used in Pharmaceutical Industry:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a key intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a building block for the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the field of organic chemistry, 2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a starting material for the synthesis of a range of chemical compounds, including dyes, pigments, and other specialty chemicals. Its reactivity and functional groups make it a versatile compound for creating diverse products.
Used in Antimicrobial Applications:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a precursor for the synthesis of indazole derivatives, which exhibit antibacterial activity. These derivatives can be utilized in the development of new antibiotics to combat drug-resistant bacterial strains.
Used in Inhibitor Development:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is also used in the synthesis of compounds that act as inhibitors of DNA gyrase B, an enzyme involved in bacterial DNA replication. Inhibitors targeting this enzyme can potentially be used in the development of new antibacterial agents.

InChI:InChI=1/C7H4Cl2O2/c8-4-1-6(9)5(3-10)7(11)2-4/h1-3,11H

Upstream product

• 874-42-0 2,4-dichlorobenzaldeyhde 
• 2420-26-0 4-chlorosalicylaldehyde 
• 68-12-2 N,N-dimethyl-formamide 

Relevant academic research and scientific papers

Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group

The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.

Efficient two-step synthesis of salicylaldehydes via directed ortho-lithiation of in situ N-silylated O-aryl N-isopropylcarbamates

O-Aryl N-isopropylcarbamates, conveniently prepared from phenols and isopropyl isocyanate, are subjected to an efficient ortho-lithiation protocol to afford the corresponding salicylaldehydes in a one-pot operation in high yields. Georg Thieme Verlag Stuttgart.

Pyrazolopyrimidines as therapeutic agents

The present invention is directed to pyrazolopyrimidine derivatives of formula (I) wherein the substituents are defined herein, which are useful as kinase inhibitors and as such are useful for affecting angiogenesis and diseases and conditions associated with angiogenesis.

Non-metallocene compounds, method for the production thereof and use of the same for the polymerisation of olefins

The invention relates to a method for producing special transition metal compounds, to novel transition metal compounds and to the use of the same for the polymerisation of olefins.

Pyrazolopyrimidines as therapeutic agents

The present invention provides compounds of Formula I, including pharmaceutically acceptable salts and/or prodrugs thereof, where G, R2, and R3 are defined as described herein.