ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

Base Information

Chemical Name:ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate
CAS No.:1350469-25-8
Molecular Formula:C₄₀H₄₁N₃O₈
Molecular Weight:691.781
Hs Code.:

ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

Synonyms:ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

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Chemical Property of ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

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Technology Process of ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

There total 18 articles about ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: C₁₆H₁₅ClO₂

: 1350469-24-7
ethyl (1R)-1-({2-[4-amino-3-(dimethylcarbamoyl)phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

: 1350469-25-8
ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 83.0%

: 1350468-50-6
ethyl (R)-1-(hydroxymethyl)-2-methyl-3-oxoisoindoline-1-carboxylate

: 1350469-53-2
[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetic acid

: 1350469-25-8
ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethyl acetate; at 20 ℃; for 23h;

Reference yield:

: 408366-55-2
4’-isopropoxy-2-biphenylcarboxylic acid

: 1350469-25-8
ethyl (1R)-1-({2-[3-(dimethylcarbamoyl)-4-{[(4'-isopropoxybiphenyl-2-yl)carbonyl]amino}phenyl]acetoxy}methyl)-2-methyl-3-oxoisoindoline-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C

With oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In dichloromethane;