Decitabine iMpurity 4

Base Information

Chemical Name:Decitabine iMpurity 4
CAS No.:863396-35-4
Molecular Formula:C₆H₁₂O₄
Molecular Weight:148.159
Hs Code.:
Mol file:863396-35-4.mol

Synonyms:methyl-2-deoxyribopyranoside

Suppliers and Price of Decitabine iMpurity 4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-deoxy-D-erythro-pentopyranoside(DecitabineImpurity(Mixtureofα/βisomers)
10g
$ 1175.00

Biosynth Carbosynth
Methyl 2-deoxy-D-ribopyranoside
250 mg
$ 75.00

Total 4 raw suppliers

Chemical Property of Decitabine iMpurity 4

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Methyl2-deoxy-D-erythro-pentopyranoside(DecitabineImpurity(Mixtureofα/βisomers) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Methyl 2-deoxy-D-erythro-pentopyranoside is an impurity of Decitabine (α-isomer: D226730), a DNA hypomethylating agent that is used to treat various forms of cancer, such as myelogeneous leukemia and metastatic lung cancerBy inhibiting DNA methyltransferase, Decitabine silences the tumour suppressor genes and, consequently, “normalizing” gene expression in cancerous cells.

Technology Process of Decitabine iMpurity 4

There total 7 articles about Decitabine iMpurity 4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 67-56-1
methanol

: 533-67-5
2-Deoxy-D-ribose

: 863396-35-4
methyl-2-deoxyribopyranoside

Guidance literature:: With hydrogenchloride;
DOI:10.1055/s-2006-950401

Reference yield:

: 67-56-1
methanol

: 533-67-5
2-Deoxy-D-ribose

: 863396-35-4
methyl-2-deoxyribopyranoside

: 51255-17-5,51255-18-6,60134-26-1,89577-26-4,96038-80-1,96039-31-5,144301-84-8,144301-85-9
1-O-methyl-2-deoxy-D-ribofuranoside

Guidance literature:: With hydrogenchloride; In diethyl ether; at 20 ℃; Product distribution / selectivity;

Reference yield:

: 67-56-1
methanol

: 22900-10-3,35536-75-5,36792-85-5,113890-34-9,113890-37-2,133813-23-7
2-deoxy-D-ribose

: 863396-35-4
methyl-2-deoxyribopyranoside

: 51255-17-5,51255-18-6,60134-26-1,89577-26-4,96038-80-1,96039-31-5,144301-84-8,144301-85-9
1-O-methyl-2-deoxy-D-ribofuranoside

Guidance literature:: methanol; With acetyl chloride; at 20 ℃; Inert atmosphere;

2-deoxy-D-ribose; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2009.08.035