2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Base Information

Chemical Name:2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol
CAS No.:1384984-28-4
Molecular Formula:C₁₇H₁₉FN₄O₄
Molecular Weight:362.361
Hs Code.:

Synonyms:2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Suppliers and Price of 2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-{5-[4-Amino-2-fluoro-5-nitro-3-(oxolan-2-yl)phenyl]pyrimidin-2-yl}propan-2-ol 95%+
1g
$ 4500.00

Chemenu
2-{5-[4-Amino-2-fluoro-5-nitro-3-(oxolan-2-yl)phenyl]pyrimidin-2-yl}propan-2-ol 95%+
250mg
$ 2315.00

Chemenu
2-{5-[4-Amino-2-fluoro-5-nitro-3-(oxolan-2-yl)phenyl]pyrimidin-2-yl}propan-2-ol 95%+
100mg
$ 1459.00

Total 3 raw suppliers

Chemical Property of 2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-{5-[4-Amino-2-fluoro-5-nitro-3-(oxolan-2-yl)phenyl]pyrimidin-2-yl}propan-2-ol 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

There total 6 articles about 2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1319255-87-2
2-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)propan-2-ol

: 1384984-27-3
4-bromo-3-fluoro-6-nitro-2-(tetrahydrofuran-2-yl)aniline

: 1384984-28-4
2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Guidance literature:: With sodium hydrogencarbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; water; Inert atmosphere; Reflux;

Reference yield:

: 1384984-24-0
3-fluoro-2-(tetrahydrofuran-2-yl)aniline

: 1384984-28-4
2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Guidance literature:: Multi-step reaction with 4 steps

1: aniline; N-Bromosuccinimide; sodium thiosulfate / ethyl acetate; hexane; tert-butyl methyl ether

2: trifluoroacetic anhydride; NH₄NO₃ / tetrahydrofuran

3: sulfuric acid

4: sodium hydrogencarbonate; nitrogen / dichloromethane; 1,4-dioxane

With N-Bromosuccinimide; NH₄NO₃; sulfuric acid; nitrogen; sodium hydrogencarbonate; sodium thiosulfate; aniline; trifluoroacetic anhydride; In tetrahydrofuran; 1,4-dioxane; hexane; dichloromethane; tert-butyl methyl ether; ethyl acetate;

Reference yield:

: 1384984-25-1
4-bromo-3-fluoro-2-(tetrahydrofuran-2-yl)aniline

: 1384984-28-4
2-[5-(4-amino-2-fluoro-5-nitro-3-tetrahydrofuran-2-yl-phenyl)pyrimidin-2-yl]propan-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic anhydride; NH₄NO₃ / tetrahydrofuran

2: sulfuric acid

3: sodium hydrogencarbonate; nitrogen / dichloromethane; 1,4-dioxane

With NH₄NO₃; sulfuric acid; nitrogen; sodium hydrogencarbonate; trifluoroacetic anhydride; In tetrahydrofuran; 1,4-dioxane; dichloromethane;