2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline

Base Information

Chemical Name:2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline
CAS No.:61001-04-5
Molecular Formula:C18H14N2
Molecular Weight:258.323
Hs Code.:
UNII:E32AQF9ESD
Nikkaji Number:J61.467J
Mol file:61001-04-5.mol

Synonyms:2-(4-methylphenyl)imidazo[2,1-a]isoquinoline;E32AQF9ESD;UNII-E32AQF9ESD;61001-04-5;2-p-Tolyl-imidazo(2,1-a)isoquinoline;2-(4-Methylphenyl)imidazo(2,1-a)isoquinoline;Imidazo(2,1-a)isoquinoline, 2-(4-methylphenyl)-;2-p-Tolylimidazo(2,1-a)isoquinoline;Oprea1_047699;Oprea1_749179;NIOSH/NI3031000;SCHEMBL13325835;CCG-17099;STK013558;AKOS000659471;Imidazo(2,1-a)isoquinoline, 2-p-tolyl-;NI30310000;AE-848/15342290;SR-01000441898;SR-01000441898-1

Suppliers and Price of 2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-METHYLPHENYL)IMIDAZO[2,1-A]ISOQUINOLINE 95.00%
5MG
$ 498.91

Total 3 raw suppliers

Chemical Property of 2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline

Chemical Property:

PSA：17.30000
LogP:4.46290
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:258.115698455
Heavy Atom Count:20
Complexity:334

Purity/Quality:

99% ^*data from raw suppliers

2-(4-METHYLPHENYL)IMIDAZO[2,1-A]ISOQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): A reproductive hazard.
Hazard Codes:A reproductive hazard.

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=CN3C=CC4=CC=CC=C4C3=N2

Technology Process of 2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline

There total 18 articles about 2-(4-Methylphenyl)imidazo[2,1-a]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 119-65-3
isoquinoline

: 36288-37-6
4-methylbenzohydroximoyl chloride

: 70-11-1
α-bromoacetophenone

: 61001-04-5
2-(4-methylphenyl)imidazo[2,1-a]isoquinoline

Guidance literature:: With triethylamine; In acetonitrile; at 80 ℃; for 4h;
DOI:10.1016/j.tetlet.2013.04.126

Reference yield: 75.0%

: 1532-84-9
isoquinolin-1-ylamine

: 98475-04-8
1-(4-methylphenyl)-2-(p-tolylsulfonyloxy)ethanone

: 61001-04-5
2-(4-methylphenyl)imidazo[2,1-a]isoquinoline

Guidance literature:: With sodium carbonate; N-butylpyridinium tetrafluoroborate; at 20 ℃; for 1h;

Reference yield: 68.0%

: 119-65-3
isoquinoline

: 89108-49-6
1-(1-azidovinyl)-4-methyl benzene

: 61001-04-5
2-(4-methylphenyl)imidazo[2,1-a]isoquinoline

Guidance literature:: With copper(l) iodide; In acetonitrile; at 65 ℃; for 24h; regioselective reaction; Molecular sieve; Sealed tube;
DOI:10.1021/jo5021618