benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

Base Information

Chemical Name:benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate
CAS No.:252919-09-8
Molecular Formula:C₂₈H₂₈N₂O₅
Molecular Weight:472.541
Hs Code.:

Synonyms:benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

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Chemical Property of benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

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Technology Process of benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

There total 5 articles about benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40217-17-2,90719-32-7,120574-96-1,102029-44-7
(R)-4-(phenylmethyl)-2-oxazolidinone

: C₂₃H₂₇NO₆

: 252919-09-8
benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

Guidance literature:: With lithium chloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jo016086b

Reference yield:

: 100-39-0
benzyl bromide

: 252919-09-8
benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NaH / tetrahydrofuran; dimethylformamide / 20 °C

2: Et₃N / tetrahydrofuran / 1 h / -30 °C

3: 55.4 g / LiCl / tetrahydrofuran / 20 °C

With sodium hydride; triethylamine; lithium chloride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jo016086b

Reference yield:

: 252919-08-7
3-{benzyl[(benzyloxy)carbonyl]amino}propanoic acid

: 252919-09-8
benzyl benzyl{3-[(4R)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3-oxopropyl}carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / tetrahydrofuran / 1 h / -30 °C

2: 55.4 g / LiCl / tetrahydrofuran / 20 °C

With triethylamine; lithium chloride; In tetrahydrofuran;
DOI:10.1021/jo016086b