1-Ethyl-3,3-dimethyl-2-methyleneindoline

Base Information

• Chemical Name: 1-Ethyl-3,3-dimethyl-2-methyleneindoline
• CAS No.: 73718-62-4
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID80501323
• Nikkaji Number: J28.031C
• Wikidata: Q72475860
• Mol file: 73718-62-4.mol

Synonyms:1-Ethyl-3,3-dimethyl-2-methyleneindoline;73718-62-4;1-ETHYL-3,3-DIMETHYL-2-METHYLIDENEINDOLE;3,3-Dimethyl-1-ethyl-2-methyleneindoline;1H-Indole,1-ethyl-2,3-dihydro-3,3-dimethyl-2-methylene-;SCHEMBL6091601;DTXSID80501323;AKOS006277900;SB65269;FT-0691031;1-ethyl-3,3-dimethyl-2-methylidene-2,3-dihydro-1H-indole

Chemical Property of 1-Ethyl-3,3-dimethyl-2-methyleneindoline

Chemical Property:

• Boiling Point: 258.095 °C at 760 mmHg
• Flash Point: 100.461 °C
• PSA: 3.24000
• Density: 0.996 g/cm³
• LogP: 3.38280
• Storage Temp.: 2-8°C
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 187.136099547
• Heavy Atom Count: 14
• Complexity: 242

Purity/Quality:

99% ^*data from raw suppliers

1-Ethyl-3,3-dimethyl-2-methyleneindoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN1C(=C)C(C2=CC=CC=C21)(C)C

Technology Process of 1-Ethyl-3,3-dimethyl-2-methyleneindoline

There total 7 articles about 1-Ethyl-3,3-dimethyl-2-methyleneindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1-ethyl-2,3,3-trimethylindolium iodide (14134-81-7) → 3,3-dimethyl-2-methylene-1-ethyl-2,3-dihydro-1H-indole (73718-62-4)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃; for 1h;

Reference yield:

1-ethyl-2,3,3-trimethyl-3H-indol-1-ium bromide → 3,3-dimethyl-2-methylene-1-ethyl-2,3-dihydro-1H-indole (73718-62-4)

Guidance literature:

With sodium hydroxide; In water; at 25 ℃; for 0.166667h;

Reference yield:

2,3,3-trimethylindoleniune (1640-39-7) + ethyl bromide (74-96-4) → 3,3-dimethyl-2-methylene-1-ethyl-2,3-dihydro-1H-indole (73718-62-4)

Guidance literature:

In acetonitrile; at 75 ℃; for 64h; Temperature; Inert atmosphere;

upstream raw materials:

1-ethyl-2,3,3-trimethylindolium iodide

2,3,3-trimethylindoleniune

3-methyl-butan-2-one

phenylhydrazine

Downstream raw materials:

1-ethyl-3,3-dimethyl-1,3-dihydro-spiro[indole-2,2'-pyrano[3,2-h]quinoline]

3,3-dimethyl-5'-oxo-1-ethyl-1,3-dihydrospiro<2H-indole-2,2'-pyrrolidine>

1-ethyl-2,3,3-trimethylindolium iodide

C₂₆H₂₄N₂O₃