(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

Base Information

Chemical Name:(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide
CAS No.:1304017-12-6
Molecular Formula:C₂₄H₂₀FN₅O₂S
Molecular Weight:461.52
Hs Code.:

Synonyms:(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

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Chemical Property of (E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

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Technology Process of (E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

There total 4 articles about (E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₂₃N₅O₂

: 445-05-6
5-fluoro-2-methylbenzenesulfonyl chloride

: 1304017-12-6
(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

Guidance literature:: With pyridine; at 20 - 30 ℃;

Reference yield:

: 1072-97-5
5-bromo-2-pyridylamine

: 1304017-12-6
(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: acetonitrile / 2 h / Reflux

2: sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide; water / 2 h / Reflux

3: ethanol / 4 h / 20 - 80 °C

4: pyridine / 20 - 30 °C

With pyridine; sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In ethanol; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 30384-96-4
6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde

: 1304017-12-6
(E)-N'-((6-(1H-indol-2-yl)imidazo[1,2-a]pyridin-3-yl)methylene)-5-fluoro-N,2-dimethylbenzenesulfonohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide; water / 2 h / Reflux

2: ethanol / 4 h / 20 - 80 °C

3: pyridine / 20 - 30 °C

With pyridine; sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In ethanol; water; N,N-dimethyl-formamide;