Technology Process of C19H28FN3O3
There total 7 articles about C19H28FN3O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
2-chloro-1-methyl-pyridinium iodide; triethylamine;
In
dichloromethane;
at 20 ℃;
for 48h;
Inert atmosphere;
DOI:10.1039/c1ob05332a
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: chloroform / 0 °C
2.1: aluminum (III) chloride / 1,2-dichloro-ethane / 4 h / 20 - 60 °C
3.1: sodium hypochlorite; sodium hydroxide / methanol; water / 2 h / 20 - 60 °C
4.1: ruthenium on carbon; ammonia; hydrogen / water / 144 h / 90 - 150 °C / 52505.3 Torr
5.1: sodium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C
5.2: 48 h / 20 °C
5.3: 3 - 4 h
6.1: 2-chloro-1-methyl-pyridinium iodide; triethylamine / dichloromethane / 48 h / 20 °C / Inert atmosphere
With
aluminum (III) chloride; sodium hypochlorite; ruthenium on carbon; 2-chloro-1-methyl-pyridinium iodide; ammonia; hydrogen; triethylamine; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; water; 1,2-dichloro-ethane;
2.1: Friedel Crafts acylation / 6.1: Mukaiyama reaction;
DOI:10.1039/c1ob05332a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C
1.2: 48 h / 20 °C
1.3: 3 - 4 h
2.1: 2-chloro-1-methyl-pyridinium iodide; triethylamine / dichloromethane / 48 h / 20 °C / Inert atmosphere
With
2-chloro-1-methyl-pyridinium iodide; triethylamine; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; water;
2.1: Mukaiyama reaction;
DOI:10.1039/c1ob05332a
