Technology Process of 4-(4-bromo-3,5-dimethylphenyl)butyl methanesulfonate
There total 8 articles about 4-(4-bromo-3,5-dimethylphenyl)butyl methanesulfonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 1 h / 20 °C
2: methanol; sodium tetrahydroborate / 2 h / 20 °C
3: triethylamine / dichloromethane / 2 h / 20 °C
4: N,N-dimethyl-formamide / 2 h / 80 °C
5: hydrogenchloride / water / 1 h / Reflux
6: methanol; sodium tetrahydroborate / 2 h / 20 °C
7: triethylamine / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; triethylamine;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 °C
1.2: 0.5 h / 0 °C
2.1: palladium on activated charcoal; hydrogen / tetrahydrofuran / 1 h / 20 °C
3.1: methanol; sodium tetrahydroborate / 2 h / 20 °C
4.1: triethylamine / dichloromethane / 2 h / 20 °C
5.1: N,N-dimethyl-formamide / 2 h / 80 °C
6.1: hydrogenchloride / water / 1 h / Reflux
7.1: methanol; sodium tetrahydroborate / 2 h / 20 °C
8.1: triethylamine / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; palladium on activated charcoal; hydrogen; sodium hydride; triethylamine;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
