(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

Base Information

Chemical Name:(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol
CAS No.:920749-68-4
Molecular Formula:C₃₆H₆₄O₃Si
Molecular Weight:572.988
Hs Code.:

Synonyms:(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

Suppliers and Price of (Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

There total 1 articles about (Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: {8-Benzyloxy-4-[1-iodo-meth-(Z)-ylidene]-octyloxy}-triisopropyl-silane

: 80434-59-9,485843-44-5,796865-68-4
(1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarboxaldehyde

: 920749-68-4
(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

Guidance literature:: {8-Benzyloxy-4-[1-iodo-meth-(Z)-ylidene]-octyloxy}-triisopropyl-silane; With n-butyllithium; In diethyl ether; Petroleum ether; at -78 - 20 ℃; for 1h;

(1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarboxaldehyde; With trimethylaluminum; In diethyl ether; Petroleum ether; at -78 - 20 ℃;
DOI:10.1016/j.jorganchem.2006.07.028

Reference yield: 99.0%

: 920749-68-4
(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

: 3019-71-4
Trichloroacetyl isocyanate

: 920749-75-3
{(S)-8-Benzyloxy-4-isocyanato-4-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-octyloxy}-triisopropyl-silane

Guidance literature:: (Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol; Trichloroacetyl isocyanate; In dichloromethane; at 0 ℃; for 1h;

With potassium carbonate; In methanol; water; at 0 - 20 ℃;

With triethylamine; trifluoroacetic anhydride; In dichloromethane; at 0 ℃; for 0.25h;
DOI:10.1016/j.jorganchem.2006.07.028

Reference yield:

: 920749-68-4
(Z)-(S)-7-Benzyloxy-1-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-3-(3-triisopropylsilanyloxy-propyl)-hept-2-en-1-ol

: (S)-5-(4-Benzyloxy-butyl)-3-methyl-5-(3-triisopropylsilanyloxy-propyl)-1,5-dihydro-pyrrol-2-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: CH₂Cl₂ / 1 h / 0 °C

1.2: potassium carbonate / methanol; H₂O / 0 - 20 °C

1.3: 99 percent / TFAA; triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

2.1: Ti(Ot-Bu)4 / benzene / 3 h / Heating

3.1: 506 mg / piperidine / dimethylformamide; CH₂Cl₂ / 20 °C

4.1: 36 percent / DMAP; DCC / CH₂Cl₂ / 144 h / 20 °C

5.1: 91 percent / second generation Grubbs catalyst / toluene / 0.5 h / Heating

With piperidine; titanium(IV) tetrabutoxide; dmap; dicyclohexyl-carbodiimide; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1016/j.jorganchem.2006.07.028