(4′-methoxylbiphenyl-2-yl)(phenyl)methanone

Base Information

• Chemical Name: (4′-methoxylbiphenyl-2-yl)(phenyl)methanone
• CAS No.: 851591-16-7
• Molecular Formula: C₂₀H₁₆O₂
• Molecular Weight: 288.346
• Mol file: 851591-16-7.mol

Synonyms:(4′-methoxylbiphenyl-2-yl)(phenyl)methanone

Chemical Property of (4′-methoxylbiphenyl-2-yl)(phenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (4′-methoxylbiphenyl-2-yl)(phenyl)methanone

There total 17 articles about (4′-methoxylbiphenyl-2-yl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(2-chlorophenyl)(phenyl)methanone (5162-03-8) + 4-methoxyphenyl magnesium bromide (13139-86-1) → (4′-methoxylbiphenyl-2-yl)(phenyl)methanone (851591-16-7)

Guidance literature:

4-methoxyphenyl magnesium bromide; In tetrahydrofuran; at -20 ℃; for 0.166667h;

(2-chlorophenyl)(phenyl)methanone; With para-fluorostyrene; tetra-(n-butyl)ammonium iodide; cobalt acetylacetonate; In tetrahydrofuran; 1,2-dimethoxyethane; at 25 ℃; for 1h;

DOI:10.1002/anie.200500099

Reference yield: 98.0%

o-bromobenzophenone (13047-06-8) + 4-methoxyphenylboronic acid (5720-07-0) → (4′-methoxylbiphenyl-2-yl)(phenyl)methanone (851591-16-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; water; toluene; for 12h; Inert atmosphere; Reflux;

DOI:10.1039/c3cc47696k

Reference yield: 98.0%

→ (4′-methoxylbiphenyl-2-yl)(phenyl)methanone (851591-16-7)

Guidance literature:

Product distribution / selectivity;

upstream raw materials:

(2-chlorophenyl)(phenyl)methanone

4-methoxyphenylmagnesium chloride

4-methoxyphenyl magnesium bromide

o-bromobenzophenone

Downstream raw materials:

4-methoxy-2'-(α-hydroxybenzyl)biphenyl

(Z)-1,2-bis[4'-methoxy-(1,1'-biphenyl)-4-yl]-1,2-diphenylethene

3-methoxy-6-phenylphenanthridine