6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline

Base Information

• Chemical Name: 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline
• CAS No.: 1283751-74-5
• Molecular Formula: C₂₁H₁₇N₃O₃
• Molecular Weight: 359.384
• Mol file: 1283751-74-5.mol

Synonyms:6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline

Chemical Property of 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline

There total 2 articles about 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-methoxy-benzaldehyde (123-11-5) + 2-amino-5-nitrobenzophenone (1775-95-7) → 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline (1283751-74-5)

Guidance literature:

With ammonium acetate; In ethanol; for 2.33333h; Reflux; Green chemistry;

DOI:10.1016/j.tetlet.2015.09.125

Reference yield:

4-methoxy-benzaldehyde (123-11-5) + 2-amino-5-nitrobenzophenone (1775-95-7) → 6-nitro-2-(4-methoxyphenyl)-4-phenyl-1,2-dihydroquinazoline (1283751-74-5) + 6-nitro-2-(4-methoxyphenyl)-4-phenylquinazoline (1283751-85-8)

Guidance literature:

With urea; at 140 ℃; for 0.0666667h; under 8175.82 Torr; Neat (no solvent); Microwave irradiation; Closed vessel;

DOI:10.1039/c0gc00838a

upstream raw materials:

4-methoxy-benzaldehyde

2-amino-5-nitrobenzophenone