C₁₂H₁₅NO₂

Base Information

• Chemical Name: C₁₂H₁₅NO₂
• CAS No.: 1421663-97-9
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.257
• Mol file: 1421663-97-9.mol

Synonyms:C₁₂H₁₅NO₂

Chemical Property of C₁₂H₁₅NO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₅NO₂

There total 4 articles about C₁₂H₁₅NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

C14H17NO3 (1421663-96-8) → C12H15NO2 (1421663-97-9)

Guidance literature:

C₁₄H₁₇NO₃; With cobalt(II) chloride hexahydrate; In tetrahydrofuran; water; isopropyl alcohol; at 20 ℃;

With sodium tetrahydroborate; In tetrahydrofuran; water; isopropyl alcohol; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1139/cjc-2012-0340

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → C12H15NO2 (1421663-97-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetic acid; ammonium acetate / toluene / 2 h / Dean-Stark; Inert atmosphere; Reflux

2.1: lithium diisopropyl amide / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 2 h / 0 °C / Inert atmosphere

3.1: sodium chloride / water; dimethyl sulfoxide / 2.5 h / 180 °C / Inert atmosphere

4.1: cobalt(II) chloride hexahydrate / tetrahydrofuran; water; isopropyl alcohol / 20 °C

4.2: 0 - 20 °C / Inert atmosphere

With cobalt(II) chloride hexahydrate; ammonium acetate; acetic acid; sodium chloride; lithium diisopropyl amide; In tetrahydrofuran; hexane; water; dimethyl sulfoxide; isopropyl alcohol; toluene;

DOI:10.1139/cjc-2012-0340

Reference yield:

diethyl 2-cyano-3-(4-methoxyphenyl)pentanedioate → C12H15NO2 (1421663-97-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium chloride / water; dimethyl sulfoxide / 2.5 h / 180 °C / Inert atmosphere

2.1: cobalt(II) chloride hexahydrate / tetrahydrofuran; water; isopropyl alcohol / 20 °C

2.2: 0 - 20 °C / Inert atmosphere

With cobalt(II) chloride hexahydrate; sodium chloride; In tetrahydrofuran; water; dimethyl sulfoxide; isopropyl alcohol;

DOI:10.1139/cjc-2012-0340

upstream raw materials:

4-methoxy-benzaldehyde

ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate

C₁₄H₁₇NO₃

Downstream raw materials:

C₂₄H₄₇NO₄SSi₂

C₂₉H₅₅NO₆SSi₂

(1E)-N-[1-[[[5-(1,1-dimethylethyl)dimethylsilyl]oxy]-3-[[4-(1,1-dimethylethyl)dimethylsilyl]-oxy]-phenyl]pentyl]-1,3-butadiene-1-sulfonamide

C₁₃H₁₇NO₄S