Technology Process of C29H35F2N5O6S2
There total 6 articles about C29H35F2N5O6S2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-[(2R,3S)-2-(2,5-difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester; C13H16N4O3S2;
With
acetic acid;
In
N,N-dimethyl acetamide;
for 0.25h;
Inert atmosphere;
With
sodium tris(acetoxy)borohydride;
In
N,N-dimethyl acetamide;
at 0 - 20 ℃;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere
1.2: 1 h / 0 °C
2.1: dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
3.1: methanol / chloroform
4.1: acetic acid / N,N-dimethyl acetamide / 0.25 h / Inert atmosphere
4.2: 0 - 20 °C
With
methanol; sodium hydride; acetic acid;
In
tetrahydrofuran; dichloromethane; chloroform; N,N-dimethyl acetamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine / tetrahydrofuran; N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran; mineral oil / 2 h / 0 - 20 °C / Inert atmosphere
2.2: 1 h / 0 °C
3.1: dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere
4.1: methanol / chloroform
5.1: acetic acid / N,N-dimethyl acetamide / 0.25 h / Inert atmosphere
5.2: 0 - 20 °C
With
methanol; sodium hydride; acetic acid; triethylamine;
In
tetrahydrofuran; dichloromethane; chloroform; N,N-dimethyl acetamide; N,N-dimethyl-formamide; mineral oil;