isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

Base Information

Chemical Name:isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate
CAS No.:178610-79-2
Molecular Formula:C₂₄H₂₉NO₇
Molecular Weight:443.497
Hs Code.:

Synonyms:isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

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Chemical Property of isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

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Technology Process of isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

There total 1 articles about isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 108-05-4,9003-20-7
vinyl acetate

: 178610-77-0
isopropyl 5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

: 178610-79-2
isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

: 178610-78-1
isopropyl (R)-(+)-2-acetoxy-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]valerate

Guidance literature:: With immobilized lipase from Pseudomonas sp; In toluene; at 23 ℃; for 4h;
DOI:10.1021/jm010490l

Reference yield: 91.0%

: 67-56-1
methanol

: 178610-79-2
isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

: 178610-82-7
methyl (S)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

Guidance literature:: With hydrogenchloride; at 20 ℃;
DOI:10.1021/jm010490l

Reference yield:

: 178610-79-2
isopropyl (S)-(-)-5-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]-2-hydroxyvalerate

: (S)-(-)-5-[3-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3-methoxyphenyl]propyl]-2,4-oxazolidinedione

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / HCl / 20 °C

2: pyridine / 20 °C

3: NH₃ / tetrahydrofuran / -65 °C

4: 1,8-diazabicyclo[5,4,0]undec-7-ene / CHCl₃ / 0 °C

With pyridine; hydrogenchloride; ammonia; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; chloroform;
DOI:10.1021/jm010490l