dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Base Information

Chemical Name:dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate
CAS No.:1332895-42-7
Molecular Formula:C₃₄H₃₈NO₅P
Molecular Weight:571.653
Hs Code.:

Synonyms:dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Suppliers and Price of dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

There total 5 articles about dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 1332895-38-1
diethyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

: 6738-17-6
O-benzyl-N,N'-dicyclohexylisourea

: 1332895-42-7
dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Guidance literature:: diethyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate; With trimethylsilyl bromide; In dichloromethane; at 0 - 20 ℃; for 24h;

With water; In tetrahydrofuran; at 20 ℃;

O-benzyl-N,N'-dicyclohexylisourea; In benzene; at 80 ℃;
DOI:10.1021/jm200694q

Reference yield:

: 1155705-57-9
diethyl 4-oxo-1-phenylbutylphosphonate

: 1332895-42-7
dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: selenium(IV) oxide; dihydrogen peroxide / tetrahydrofuran / 4 h / 65 °C

2.1: oxalyl dichloride / N,N-dimethyl-formamide; toluene / 2 h / 0 - 20 °C

2.2: 20 °C

3.1: trimethylsilyl bromide / dichloromethane / 24 h / 0 - 20 °C

3.2: 20 °C

3.3: 80 °C

With selenium(IV) oxide; oxalyl dichloride; trimethylsilyl bromide; dihydrogen peroxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm200694q

Reference yield:

: 1258145-84-4
C₁₆H₂₅O₅P

: 1332895-42-7
dibenzyl {4-[(benzyloxy)(propan-2-yl)amino]-4-oxo-1-phenylbutyl}phosphonate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride / water; acetone / 3 h / 50 °C

2.1: selenium(IV) oxide; dihydrogen peroxide / tetrahydrofuran / 4 h / 65 °C

3.1: oxalyl dichloride / N,N-dimethyl-formamide; toluene / 2 h / 0 - 20 °C

3.2: 20 °C

4.1: trimethylsilyl bromide / dichloromethane / 24 h / 0 - 20 °C

4.2: 20 °C

4.3: 80 °C

With hydrogenchloride; selenium(IV) oxide; oxalyl dichloride; trimethylsilyl bromide; dihydrogen peroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1021/jm200694q