5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione

Base Information

• Chemical Name: 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione
• CAS No.: 162610-46-0
• Molecular Formula: C₆H₆OS₅
• Molecular Weight: 254.443
• Mol file: 162610-46-0.mol

Synonyms:5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione

Chemical Property of 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione

Chemical Property:

Purity/Quality:

5-(HYDROXYMETHYL)-5,6-DIHYDRO[1,3]DITHIOLO[4,5-B][1,4]DITHIINE-2-THIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione

There total 4 articles about 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

allyl alcohol (107-18-6) + 1,3-dithiol-2,4,5-trithione (85931-57-3,123399-69-9) → 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione (162610-46-0)

Guidance literature:

In toluene; for 4h; Heating;

DOI:10.1039/b606715h

Reference yield: 68.0%

allyl alcohol (107-18-6) → 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione (162610-46-0)

Guidance literature:

In benzene; for 5h; Heating;

DOI:10.1007/BF01165712

Reference yield: 50.0%

2,3-Dibromopropan-1-ol (96-13-9) + [bis(1,3-dithiole-2-thione-4,5-dithiolato)zincate(II)] → 5,6-dihydro-5-(hydroxymethyl)-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione (162610-46-0)

Guidance literature:

In acetone; at 70 - 80 ℃; for 4h;

DOI:10.1016/S0040-4020(97)00732-1

upstream raw materials:

4,5-bis(benzoylthio)-1,3-dithiole-2-thione

2,3-Dibromopropan-1-ol

allyl alcohol

1,3-dithiol-2,4,5-trithione

Downstream raw materials:

5-(tert-butyldiphenylsilyloxymethyl)-5,6-dihydro-1,3-dithiolo[4,5-b][1,4]dithiine-2-thione

5,6-dihydro-5-(4'-methylbenzenesulfonyloxy)-methyl-1,3-dithiolo-[4,5-b]-1,4-dithiin-2-thione

5-(t-butyldiphenylsilyloxy)methyl-5,6-dihydro-2-(5',6'-dihydro-1,3-dithiolo[4,5-b]-1,4-dithiin-2'-ylidene)-1,3-dithiolo[4,5-b]-1,4-dithiin

[2-(4,5-bis-methylsulfanyl-[1,3]dithiol-2-ylidene)-5,6-dihydro-[1,3]dithiolo[4,5-b][1,4]dithiin-5-ylmethoxy]-tert-butyl-diphenyl-silane