2-Piperidinoisonicotinic acid

Base Information

Chemical Name:2-Piperidinoisonicotinic acid
CAS No.:855153-75-2
Molecular Formula:C11H14 N2 O2
Molecular Weight:206.244
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50424434
Wikidata:Q82237010
Mol file:855153-75-2.mol

Synonyms:855153-75-2;2-Piperidinoisonicotinic acid;2-(Piperidin-1-yl)isonicotinic acid;3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxylic acid;2-piperidin-1-ylpyridine-4-carboxylic acid;2-(piperidin-1-yl)pyridine-4-carboxylic acid;2-Piperidin-1-ylisonicotinic acid;2-PIPERIDIN-1-YLPYRIDIN-4-YLCARBOXYLIC ACID;SCHEMBL1255519;DTXSID50424434;PYHYIVXTQSCHDX-UHFFFAOYSA-N;2-(Piperidin-1-yl)isonicotinicacid;2-Piperidin-1-yl-isonicotinic acid;MFCD04115214;2-PIPERDIN-YLISONICOTINIC ACID;AKOS000214820;AB19706;PS-4123;2-Piperidinoisonicotinic acid, AldrichCPR;CS-0271820;FT-0742004;E86888;EN300-703454;A1-01374;2-PIPERIDIN-1-YLISONICOTIC ACID 97%2-PIPERIDIN-1-YLPYRIDIN-4-YLCARBOXYLIC ACID

Suppliers and Price of 2-Piperidinoisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-(Piperidin-1-yl)isonicotinic acid 97.0%
1 g
$ 272.00

SynQuest Laboratories
2-(Piperidin-1-yl)isonicotinic acid 97.0%
100 mg
$ 48.00

Matrix Scientific
3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxylic acid
500mg
$ 182.00

J&W Pharmlab
3,4,5,6-Tetrahydro-2H-[1,2'']bipyridinyl-4''-carboxylicacid 96%
250mg
$ 149.00

J&W Pharmlab
3,4,5,6-Tetrahydro-2H-[1,2'']bipyridinyl-4''-carboxylicacid 96%
1g
$ 298.00

Crysdot
2-(Piperidin-1-yl)isonicotinicacid 95+%
5g
$ 671.00

Chemenu
3,4,5,6-Tetrahydro-2H-[1,2'']bipyridinyl-4''-carboxylicacid 95%
5g
$ 634.00

Atlantic Research Chemicals
2-Piperidin-1-ylisonicotinicacid 95%
1gm:
$ 215.61

Apolloscientific
2-(Piperidin-1-yl)isonicotinicacid 97%
100mg
$ 44.00

Apolloscientific
2-(Piperidin-1-yl)isonicotinicacid 97%
1g
$ 247.00

Total 12 raw suppliers

Chemical Property of 2-Piperidinoisonicotinic acid

Chemical Property:

Vapor Pressure:7.09E-10mmHg at 25°C
Melting Point:167-168.5
Boiling Point:476.2°C at 760 mmHg
Flash Point:241.8°C
PSA：53.43000
Density:1.231g/cm³
LogP:1.83510
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:206.105527694
Heavy Atom Count:15
Complexity:227

Purity/Quality:

97% ^*data from raw suppliers

2-(Piperidin-1-yl)isonicotinic acid 97.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=NC=CC(=C2)C(=O)O

Technology Process of 2-Piperidinoisonicotinic acid

There total 1 articles about 2-Piperidinoisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 110-89-4
piperidine

: 66572-56-3
2-bromoisonicotinic acid

: 855153-75-2
2-(piperidin-1-yl)isonicotinic acid

Guidance literature:: at 105 ℃; for 24h; Heating / reflux;

Reference yield:

: 855153-75-2
2-(piperidin-1-yl)isonicotinic acid

: 888070-04-0
(2-piperidin-1-yl pyridin-4-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 20 h / 0 °C / Heating / reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C

2.2: -20 °C

With lithium aluminium tetrahydride; thionyl chloride; In tetrahydrofuran;