Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate

Base Information

Chemical Name:Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate
CAS No.:888070-05-1
Molecular Formula:C12H16 N2 O2
Molecular Weight:220.271
Hs Code.:
DSSTox Substance ID:DTXSID60594596
Wikidata:Q82489488
Mol file:888070-05-1.mol

Synonyms:888070-05-1;methyl 2-(piperidin-1-yl)pyridine-4-carboxylate;methyl 2-piperidin-1-ylpyridine-4-carboxylate;4-Pyridinecarboxylicacid, 2-(1-piperidinyl)-, methyl ester;Methyl 2-piperidin-1-ylpyridin-4-ylcarboxylate;methyl 2-piperidinoisonicotinate;SCHEMBL3750019;DTXSID60594596;CCOBIXWZODVNKL-UHFFFAOYSA-N;Methyl 2-piperidin-1-ylisonicotinate;MFCD08741429;MS-22690;4-Pyridinecarboxylicacid,2-(1-piperidinyl)-,methyl ester;METHYL 2-PIPERIDIN-1-YLISONICOTINATE 97+%METHYL 2-PIPERIDIN-1-YLPYRIDIN-4-YLCARBOXYLATE

Suppliers and Price of Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl2-piperidinoisonicotinate
50mg
$ 65.00

American Custom Chemicals Corporation
METHYL 2-PIPERIDIN-1-YLISONICOTINATE 95.00%
1G
$ 675.00

American Custom Chemicals Corporation
METHYL 2-PIPERIDIN-1-YLISONICOTINATE 95.00%
250MG
$ 616.79

Advanced Chemicals Intermediatesced Chemicals Intermediates
3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxylicacidmethylester 95%+
1g
$ 152.25

Acints
3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxylicacidmethylester 95%+
1g
$ 152.25

Total 4 raw suppliers

Chemical Property of Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate

Chemical Property:

Vapor Pressure:9.93E-06mmHg at 25°C
Boiling Point:372°C at 760 mmHg
Flash Point:178.8°C
PSA：42.43000
Density:1.142g/cm³
LogP:1.92350
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:239

Purity/Quality:

98%min ^*data from raw suppliers

methyl2-piperidinoisonicotinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=NC=C1)N2CCCCC2

Technology Process of Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate

There total 1 articles about Methyl 2-(piperidin-1-yl)pyridine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66572-56-3
2-bromoisonicotinic acid

: 888070-05-1
methyl 2-piperidin-1-ylisonicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: 24 h / 105 °C / Heating / reflux

2: thionyl chloride / 20 h / 0 °C / Heating / reflux

With thionyl chloride;

Reference yield: 65.0%

: 888070-05-1
methyl 2-piperidin-1-ylisonicotinate

: 888070-04-0
(2-piperidin-1-yl pyridin-4-yl)methanol

Guidance literature:: methyl 2-piperidin-1-ylisonicotinate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

With sodium hydroxide; water; In tetrahydrofuran; at -20 ℃;