3-acetamido-4-nitrophthalic acid

Base Information

• Chemical Name: 3-acetamido-4-nitrophthalic acid
• CAS No.: 209324-65-2
• Molecular Formula: C₁₀H₈N₂O₇
• Molecular Weight: 268.183
• Mol file: 209324-65-2.mol

Synonyms:3-acetamido-4-nitrophthalic acid

Chemical Property of 3-acetamido-4-nitrophthalic acid

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-acetamido-4-nitrophthalic acid

There total 2 articles about 3-acetamido-4-nitrophthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2,3-dimethyl-6-nitroacetanilide (138330-47-9) → 3-acetamido-4-nitrophthalic acid (209324-65-2)

Guidance literature:

With potassium permanganate; magnesium sulfate; In water; Heating;

DOI:10.1021/ac9801723

Reference yield:

2,3-dimethyl-6-nitroaniline (59146-96-2) → 3-acetamido-4-nitrophthalic acid (209324-65-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / acetic acid / 1 h / Heating

2: 52 percent / KMnO₄; MgSO₄ / H₂O / Heating

With potassium permanganate; magnesium sulfate; In water; acetic acid; 1: Substitution / 2: Oxidation;

DOI:10.1021/ac9801723

Reference yield: 58.0%

acetyl chloride (75-36-5) + 3-acetamido-4-nitrophthalic acid (209324-65-2) → 3-acetamido-4-nitrophthalic anhydride (209324-66-3)

Guidance literature:

In dichloromethane; acetic anhydride;

upstream raw materials:

2,3-dimethyl-6-nitroacetanilide

2,3-dimethyl-6-nitroaniline

Downstream raw materials:

3-acetamido-4-nitrophthalic anhydride