Technology Process of tBOC-Gly-ΔPhe-(S)-Leu-OMe
There total 8 articles about tBOC-Gly-ΔPhe-(S)-Leu-OMe which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: DCC / pyridine; CH2Cl2
2: 1.) N-methylmorpholine (NMM) 2.) 1M methylpiperidine (NMP) / 1.) at pH9, 4h
With
4-methyl-morpholine; N-methylcyclohexylamine; dicyclohexyl-carbodiimide;
In
pyridine; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1-hydroxybenzotriazole, N-methylmorpholine, N,N-dicyclohexylcarbodiimide / dimethylformamide
2: 1N NaOH / H2O; methanol
3: NaOAc, Ac2O
4: Et3N / CHCl3
With
4-methyl-morpholine; sodium hydroxide; sodium acetate; acetic anhydride; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide;
In
methanol; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)82412-1
