(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Base Information

Chemical Name:(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol
CAS No.:211861-28-8
Molecular Formula:C₃₄H₅₁NO₂
Molecular Weight:505.784
Hs Code.:

Synonyms:(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Suppliers and Price of (2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

There total 12 articles about (2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1826-67-1
vinyl magnesium bromide

: 209003-93-0
(3R,5S,8R,8aR)-8-Benzyloxy-5-dodecyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine

: 211861-28-8
(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Guidance literature:: In tetrahydrofuran; for 15h; Ambient temperature;
DOI:10.1016/S0040-4020(98)00508-0

Reference yield:

: 164530-43-2
Weinreb amide

: 211861-28-8
(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Guidance literature:: Multi-step reaction with 9 steps

1: tetrahydrofuran / Ambient temperature

2: NaBH₄ / ethanol / -78 °C

3: 98 percent / NaH, N(Bu₄)I / tetrahydrofuran / Ambient temperature

4: 78 percent / NaIO₄ / OsO₄ / tetrahydrofuran; H₂O / Ambient temperature

5: diethyl ether / Ambient temperature

6: PDC / CH₂Cl₂ / Ambient temperature

7: 1.) CF₃COOH / 1.) ClCH₂CH₂Cl, rt.; 2.) water

8: 1.) AgBF₄; 2.) Zn(BH₄)2 / 1.) THF, -78 deg C

9: 86 percent / tetrahydrofuran / Ambient temperature

With sodium tetrahydroborate; sodium periodate; dipyridinium dichromate; silver tetrafluoroborate; zinc(II) tetrahydroborate; tetra-(n-butyl)ammonium iodide; sodium hydride; trifluoroacetic acid; osmium(VIII) oxide; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1016/S0040-4039(98)00646-7

Reference yield:

: 209003-87-2
(2R,4R)-2'-pent-4'-enoyl-4-phenyloxazolidine-3-carboxylic acid tert-butyl ester

: 211861-28-8
(2S,3R,6S,1'R)-2-(3-benzyloxy-6-dodecyl-2-vinylpiperidine-1-yl)-2-phenylethanol

Guidance literature:: Multi-step reaction with 8 steps

1: NaBH₄ / ethanol / -78 °C

2: 98 percent / NaH, N(Bu₄)I / tetrahydrofuran / Ambient temperature

3: 78 percent / NaIO₄ / OsO₄ / tetrahydrofuran; H₂O / Ambient temperature

4: diethyl ether / Ambient temperature

5: PDC / CH₂Cl₂ / Ambient temperature

6: 1.) CF₃COOH / 1.) ClCH₂CH₂Cl, rt.; 2.) water

7: 1.) AgBF₄; 2.) Zn(BH₄)2 / 1.) THF, -78 deg C

8: 86 percent / tetrahydrofuran / Ambient temperature

With sodium tetrahydroborate; sodium periodate; dipyridinium dichromate; silver tetrafluoroborate; zinc(II) tetrahydroborate; tetra-(n-butyl)ammonium iodide; sodium hydride; trifluoroacetic acid; osmium(VIII) oxide; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1016/S0040-4039(98)00646-7