3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Base Information

Chemical Name:3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride
CAS No.:1258063-46-5
Molecular Formula:C₁₄H₁₅F₅N₂O*ClH
Molecular Weight:358.739
Hs Code.:

Synonyms:3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Suppliers and Price of 3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

There total 2 articles about 3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1254841-10-5
N-((6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-azepan-3-yl)acetamide

: 1258063-46-5
3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; tert-butyl methyl ether; water; at 67 - 88 ℃; Inert atmosphere;
DOI:10.1021/ol101804e

Reference yield:

: 1246403-34-8
N-((3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)-azepan-3-yl)acetamide

: 1258063-46-5
3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

Guidance literature:: With hydrogenchloride; water; In isopropyl alcohol;
DOI:10.1021/jo101704b

Reference yield: 94.6%

: 1634-04-4
tert-butyl methyl ether

: 1258063-46-5
3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride

: C₅H₁₂O*C₁₄H₁₅F₅N₂O*ClH

Guidance literature:: 3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one hydrochloride; With 5-Nitrosalicylaldehyde; triethylamine; In methanol; at 55 ℃; for 3h; Inert atmosphere;

tert-butyl methyl ether; With hydrogenchloride; In methanol; at 18 - 20 ℃;
DOI:10.1021/ol101804e