4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Base Information

Chemical Name:4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline
CAS No.:1342869-10-6
Molecular Formula:C₂₂H₁₈FN₃O₃S
Molecular Weight:423.468
Hs Code.:

Synonyms:4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

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Chemical Property of 4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Chemical Property:

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Technology Process of 4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

There total 1 articles about 4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1342869-06-0
2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)-7-chlorothieno[3,2-b]pyridine

: 1341216-35-0
3-fluoro-4-hydroxybenzenaminium chloride

: 1342869-10-6
4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide;

Reference yield:

: 1342869-10-6
4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

: 1885-14-9
phenyl chloroformate

: 765-30-0
Cyclopropylamine

: 1342869-12-8
1-(4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-3-cyclopropylurea

Guidance literature:: With pyridine; ammonium hydroxide; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; N,N-dimethyl-formamide;

Reference yield:

: 1342869-10-6
4-(2-(6-(1,3-dioxan-2-yl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluoroaniline

: 1342869-16-2
1-cyclopropyl-3-(3-fluoro-4-(2-(6-((2-oxopyrrolidin-1-yl)methyl)pyridin-3-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium hydroxide; pyridine / N,N-dimethyl-formamide; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

2: acetic acid / water

3: ammonium hydroxide; formic acid; acetic acid; sodium tris(acetoxy)borohydride / N,N-dimethyl-formamide; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

With pyridine; ammonium hydroxide; formic acid; sodium tris(acetoxy)borohydride; acetic acid; In water; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; N,N-dimethyl-formamide;