4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine

Base Information

Chemical Name:4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine
CAS No.:202199-06-2
Molecular Formula:C₂₀H₂₆N₂
Molecular Weight:294.44
Hs Code.:
ChEMBL ID:CHEMBL4444968
DSSTox Substance ID:DTXSID501186345

Synonyms:CHEMBL4444968;SCHEMBL4205093;KPAHTAFRNBMJNE-UHFFFAOYSA-N;DTXSID501186345;BDBM50535288;AKOS000237592;202199-06-2;4-((4-methylphenyl)methyl)amino-1-phenylmethylpiperidine;N-[(4-Methylphenyl)methyl]-1-(phenylmethyl)-4-piperidinamine

Suppliers and Price of 4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:294.209598838
Heavy Atom Count:22
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CNC2CCN(CC2)CC3=CC=CC=C3

Technology Process of 4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine

There total 4 articles about 4-((4-Methylphenyl)methyl)amino-1-phenylmethylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: N-(1-benzylpiperidin-4-yl)-1-(p-tolyl)methanimine

: 202199-06-2
4-((4-methylphenyl)methyl)amino-1-phenylmethylpiperidine

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 5 ℃;
DOI:10.1016/j.ejmech.2019.02.030

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 104-84-7
para-methylbenzylamine

: 202199-06-2
4-((4-methylphenyl)methyl)amino-1-phenylmethylpiperidine

Guidance literature:: With sodium borohydrid; In methanol; water;

Reference yield:

: 50541-93-0
4-amino-1-benzylpiperidine

: 104-87-0
4-methyl-benzaldehyde

: 202199-06-2
4-((4-methylphenyl)methyl)amino-1-phenylmethylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / ethanol / 20 °C

2: sodium tetrahydroborate / methanol / 0 - 5 °C

With sodium tetrahydroborate; acetic acid; In methanol; ethanol;
DOI:10.1016/j.ejmech.2019.02.030