Technology Process of 2,2-dichloro-3,3-diphenylcyclobutanone
There total 5 articles about 2,2-dichloro-3,3-diphenylcyclobutanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere; Schlenk technique
2: zinc-copper couple; trichlorophosphate / diethyl ether / 20 °C / Inert atmosphere; Schlenk technique
With
zinc-copper couple; potassium tert-butylate; trichlorophosphate;
In
tetrahydrofuran; diethyl ether;
1: |Wittig Olefination;
DOI:10.1039/c5cc01415h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: trichlorophosphate; zinc/copper couple / diethyl ether / Inert atmosphere; Reflux
With
zinc/copper couple; trichlorophosphate;
In
tetrahydrofuran; diethyl ether;
DOI:10.1021/acs.orglett.1c03938
