(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Base Information

Chemical Name:(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester
CAS No.:479035-91-1
Molecular Formula:C₂₄H₃₁FO₄SSi
Molecular Weight:462.658
Hs Code.:

Synonyms:(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Suppliers and Price of (2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

There total 5 articles about (2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 479035-90-0
(2R,4R/S)-5-tert-butyldiphenylsilyloxy-2-fluoro-4-iodopentanoic acid methyl ester

: 10387-40-3
potassium thioacetate

: 479035-91-1
(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 8h;
DOI:10.1021/jm020376i

Reference yield:

: 212954-52-4
(R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-fluoro-5H-furan-2-one

: 479035-91-1
(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/C

2: NaOH

3: I₂; PPh₃; imidazole

4: dimethylformamide

With 1H-imidazole; sodium hydroxide; hydrogen; iodine; triphenylphosphine; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1081/NCN-120021965

Reference yield:

: 398133-29-4
(2R,4R)-(-)-4-tert-butyldiphenylsilyloxymethyl-2-fluoro-γ-butyrolactone

: 479035-91-1
(2R,4R/S)-4-acetylsulfanyl-5-tert-butyldiphenylsilyloxy-2-fluoropentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH

2: I₂; PPh₃; imidazole

3: dimethylformamide

With 1H-imidazole; sodium hydroxide; iodine; triphenylphosphine; In N,N-dimethyl-formamide;
DOI:10.1081/NCN-120021965