ethyl 5-phenyl-1H-pyrrole-2-carbodithioate

Base Information

• Chemical Name: ethyl 5-phenyl-1H-pyrrole-2-carbodithioate
• CAS No.: 147915-94-4
• Molecular Formula: C₁₃H₁₃NS₂
• Molecular Weight: 247.385
• Mol file: 147915-94-4.mol

Synonyms:ethyl 5-phenyl-1H-pyrrole-2-carbodithioate

Chemical Property of ethyl 5-phenyl-1H-pyrrole-2-carbodithioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl 5-phenyl-1H-pyrrole-2-carbodithioate

There total 4 articles about ethyl 5-phenyl-1H-pyrrole-2-carbodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

carbon disulfide (75-15-0,12122-00-8) + 2-phenyl-1H-pyrrole (3042-22-6) + ethyl iodide (75-03-6) → ethyl 5-phenyl-1H-pyrrole-2-carbodithioate (147915-94-4)

Guidance literature:

2-phenyl-1H-pyrrole; With potassium hydroxide pentahydrate; In dimethyl sulfoxide; for 0.5h;

carbon disulfide; In dimethyl sulfoxide; at 20 ℃; for 2h;

ethyl iodide; In dimethyl sulfoxide; for 2h;

DOI:10.1016/j.bioorg.2020.104171

Reference yield:

ethyl iodide (75-03-6) + Potassium 5-phenylpyrrole-2-carbodithioate → Diethyl disulfide (110-81-6) + ethyl 5-phenyl-1H-pyrrole-2-carbodithioate (147915-94-4)

Guidance literature:

In dimethyl sulfoxide; for 2h; Yield given. Yields of byproduct given;

DOI:10.1007/BF00531472

Reference yield:

2-phenyl-1H-pyrrole (3042-22-6) → ethyl 5-phenyl-1H-pyrrole-2-carbodithioate (147915-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) KOH / 1.) DMSO, 30 min, 2.) DMSO, RT, 2 h

2: dimethylsulfoxide / 2 h

With potassium hydroxide; In dimethyl sulfoxide;

DOI:10.1007/BF00531472

upstream raw materials:

ethyl iodide

carbon disulfide

2-phenyl-1H-pyrrole

Downstream raw materials:

3-imino-1-(methylamino)-5-phenyl-3H-pyrrolizine-2-carbonitrile

C₁₆H₁₃N₃S

1-Ethylsulfanyl-3-oxo-5-phenyl-3H-pyrrolizine-2-carbonitrile