4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Base Information

Chemical Name:4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide
CAS No.:157465-47-9
Molecular Formula:C₁₅H₂₁NO₃
Molecular Weight:263.337
Hs Code.:
DSSTox Substance ID:DTXSID401202558

Synonyms:SCHEMBL9402804;DTXSID401202558;4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide;157465-47-9

Suppliers and Price of 4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:263.15214353
Heavy Atom Count:19
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)ONC(=O)C1=CC=C(C=C1)C(=O)C(C)(C)C

Technology Process of 4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

There total 4 articles about 4-(2,2-Dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 75-26-3
isopropyl bromide

: 139681-44-0
4-(2,2-dimethyl-1-oxopropyl)-N-hydroxybenzamide

: 157465-47-9
4-(2,2-dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Guidance literature:: With sodium hydroxide; In ethanol; for 21h; Heating;
DOI:10.1021/jm980438y

Reference yield:

: 30314-44-4
2,2-dimethyl-1-(4-methylphenyl)-1-propanone

: 157465-47-9
4-(2,2-dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 56 percent / aq. KMnO₄ / 4 h / Heating

2: 99 percent / SOCl₂ / 1.5 h / Heating

3: 82 percent / hydroxylamine hydrochloride, 2N aq. NaOH / diethyl ether / 0 °C

4: 46 percent / NaOH / ethanol / 21 h / Heating

With sodium hydroxide; potassium permanganate; thionyl chloride; hydroxylamine hydrochloride; In diethyl ether; ethanol;
DOI:10.1021/jm980438y

Reference yield:

: 32018-31-8
4-pivaloyl-benzoic acid

: 157465-47-9
4-(2,2-dimethyl-1-oxopropyl)-N-(1-methylethoxy)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / SOCl₂ / 1.5 h / Heating

2: 82 percent / hydroxylamine hydrochloride, 2N aq. NaOH / diethyl ether / 0 °C

3: 46 percent / NaOH / ethanol / 21 h / Heating

With sodium hydroxide; thionyl chloride; hydroxylamine hydrochloride; In diethyl ether; ethanol;
DOI:10.1021/jm980438y