(4-Amino-2-methylphenyl)(phenyl)methanone

Base Information

• Chemical Name: (4-Amino-2-methylphenyl)(phenyl)methanone
• CAS No.: 30086-89-6
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.263
• DSSTox Substance ID: DTXSID90511352
• Nikkaji Number: J88.642D
• Wikidata: Q82370103
• Mol file: 30086-89-6.mol

Synonyms:(4-Amino-2-methylphenyl)(phenyl)methanone;30086-89-6;SCHEMBL10625343;DTXSID90511352;AKOS013513666

Chemical Property of (4-Amino-2-methylphenyl)(phenyl)methanone

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 211.099714038
• Heavy Atom Count: 16
• Complexity: 245

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)N)C(=O)C2=CC=CC=C2

Technology Process of (4-Amino-2-methylphenyl)(phenyl)methanone

There total 3 articles about (4-Amino-2-methylphenyl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3'-methylbenzanilide (582-77-4) → 2-amino 6-methyl benzophenone (50817-58-8) + 2-amino-4-methylbenzophenone (4937-62-6) + 4-amino-2-methylbenzophenone (30086-89-6) + 1-amino-3-methylbenzene (108-44-1)

Guidance literature:

Product distribution; Irradiation; various solvents; with/without β-cyclodextrin;

DOI:10.1016/S0040-4020(01)86094-4

Reference yield:

3-Methylacetanilide (537-92-8) + benzoyl chloride (98-88-4) → 4-amino-2-methylbenzophenone (30086-89-6)

Guidance literature:

With aluminium trichloride; Erwaermen des Reaktionsprodukts mit wss. HCl;

Reference yield:

1-methyl-3-nitrobenzene (99-08-1) + phenylacetonitrile (140-29-4) → 4-amino-2-methylbenzophenone (30086-89-6)

Guidance literature:

Multistep reaction; (i) KOH, MeOH, (ii) aq. H₂O₂, (iii) (reduction);

upstream raw materials:

3-Methylacetanilide

benzoyl chloride

1-methyl-3-nitrobenzene

phenylacetonitrile