2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Base Information

Chemical Name:2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide
CAS No.:359878-17-4
Molecular Formula:C₂₃H₃₀N₂O₂
Molecular Weight:366.503
Hs Code.:
UNII:H0EVX3PS4B
Nikkaji Number:J1.617.829B
Wikipedia:AC-90179
Wikidata:Q27074140
Pharos Ligand ID:ZS9VWZML7BRB

Synonyms:2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide;2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide hydrochloride;AC 90179;AC-90179;AC90179

Suppliers and Price of 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Chemical Property:

Boiling Point:533.9±50.0 °C(Predicted)
Density:1.12±0.1 g/cm3(Predicted)
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:366.230728204
Heavy Atom Count:27
Complexity:445

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CN(C2CCN(CC2)C)C(=O)CC3=CC=C(C=C3)OC

Technology Process of 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

There total 3 articles about 2-(4-Methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 359878-18-5
1-methyl-N-(4-methylbenzyl)-piperidin-4-amine

: 4693-91-8
4-methoxyphenyl-acetic chloride

: 359878-17-4
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1002/jlcr.1124

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 359878-17-4
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / sodium borohydride / methanol / 16 h / 20 °C

2: 70 percent / triethylamine / tetrahydrofuran / 2 h / 20 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1002/jlcr.1124

Reference yield:

: 104-84-7
para-methylbenzylamine

: 359878-17-4
2-(4-methoxyphenyl)-N-(4-methylbenzyl)-N-(1-methylpiperidin-4-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / sodium borohydride / methanol / 16 h / 20 °C

2: 70 percent / triethylamine / tetrahydrofuran / 2 h / 20 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1002/jlcr.1124