N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate

Base Information

• Chemical Name: N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate
• CAS No.: 955967-49-4
• Molecular Formula: C₂HF₃O₂*C₄₁H₄₈N₁₀O₅
• Molecular Weight: 874.92
• Mol file: 955967-49-4.mol

Synonyms:N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate

Chemical Property of N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate

There total 1 articles about N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide (884652-89-5) + 6-morpholinonicotinoyl chloride (313350-36-6) + trifluoroacetic acid (76-05-1) → N-{(R)-1-[9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylaminocyclopentyl)-6-(2,2-diphenylethylamino)-9H-purin-2-yl]pyrrolidin-3-yl}-6-morpholin-4-yl-nicotinamide trifluoroacetate (955967-49-4)

Guidance literature:

N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide; 6-morpholinonicotinoyl chloride; With triethylamine; In tetrahydrofuran; at 20 ℃;

trifluoroacetic acid; In water; acetonitrile;

upstream raw materials:

N-{(1S,2R,3S,4R)-4-[2-((1S,3R)-3-amino-pyrrolidin-1-yl)-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide

6-morpholinonicotinoyl chloride

trifluoroacetic acid

Refernces