3,5-Diaminosalicylic acid

Base Information

• Chemical Name: 3,5-Diaminosalicylic acid
• CAS No.: 112725-89-0
• Molecular Formula: C7H8N2O3
• Molecular Weight: 168.152
• Hs Code.: 2922509090
• Mol file: 112725-89-0.mol

Synonyms:3,5-Diaminosalicylic acid;

Chemical Property of 3,5-Diaminosalicylic acid

Chemical Property:

• Vapor Pressure: 4.24E-09mmHg at 25°C
• Refractive Index: 1.768
• Boiling Point: 455.8 °C at 760 mmHg
• PKA: 0.96±0.14(Predicted)
• Flash Point: 229.4 °C
• PSA: 109.57000
• Density: 1.602 g/cm³
• LogP: 1.41720
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

3,5-Diamino-2-hydroxybenzoic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Diaminosalicylic acid

There total 10 articles about 3,5-Diaminosalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3,5-dinitrosalicylic acid (609-99-4) → 3,5‐diaminosalicylic acid (112725-89-0)

Guidance literature:

With formic acid; nickel; In methanol; at 20 ℃; for 0.25h;

DOI:10.1080/00397910008087439

Reference yield: 80.0%

3-amino-5-nitrosalicylic acid (831-51-6) → 3,5‐diaminosalicylic acid (112725-89-0)

Guidance literature:

With sodium tetrahydroborate; C₅₄H₅₀Cl₂N₂O₃Ru₂; In ethanol; at 20 ℃; for 3h;

DOI:10.1016/j.jorganchem.2019.120984

Reference yield:

1-methyl-2-pyridone (694-85-9,859803-97-7) + 2,2'-di(3,4-di-carboxylphenyl)hexafluoropropane dianhydride → 3,5‐diaminosalicylic acid (112725-89-0)

Guidance literature:

upstream raw materials:

methyl-3,5-dinitrosalicylate

5-amino-2-hydroxy-3-nitro-benzoic acid

phenylhydrazine

hydrogenchloride

Refernces

• 1、 Nandhini, Raja,Krishnamoorthy, Bellie Sundaram,Venkatachalam, Galmari. "Binuclear half-sandwich ruthenium(II) Schiff base complexes: Synthesis, characterization, DFT study and catalytic activity for the reduction of nitroarenes". . . Retrieved 2019/11/02.
• 2、 Arya, Kapil,Dandia, Anshu. "Selective reduction of nitro compounds using CeY zeolite under microwaves". experimental part. p. 55 - 58. Retrieved 2010/09/05.