N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline)

Base Information

• Chemical Name: N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline)
• CAS No.: 500117-04-4
• Molecular Formula: C₂₃H₁₇F₆N₃
• Molecular Weight: 449.398
• Mol file: 500117-04-4.mol

Synonyms:N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline)

Chemical Property of N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline)

There total 2 articles about N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,6-Diacetylpyridine (1129-30-2) + N?sulfinyl?2?trifluoromethylaniline (74653-65-9) → N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline) (500117-04-4)

Guidance literature:

With silica supported titanium imido complex (ΞSiO)Ti(=NtBu)(Me₂Pyr)(py)₂; In n-heptane; for 1.5h; Inert atmosphere; Schlenk technique; Reflux;

DOI:10.1002/anie.201804346

Reference yield: 52.0%

2,6-Diacetylpyridine (1129-30-2) + 2-(trifluoromethyl)benzenamine (88-17-5) → N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline) (500117-04-4)

Guidance literature:

With silica-alumina grade-135; In toluene; for 96h; Inert atmosphere; Molecular sieve;

DOI:10.1016/j.molcata.2011.03.015

Reference yield: 87.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + cobalt chloride*1,5 THF + N,N'-(1,1'-(pyridine-2,6-diyl)bis(ethan-1-yl-1-ylidene))bis(2-(trifluoromethyl)aniline) (500117-04-4) → Co(2+)*2Cl(1-)*CF3(C6H4)NC(CH3)(C5H3N)C(CH3)N(C6H4)CF3*0.5C4H8O = CoCl2C23H17F6N3*0.5C4H8O

Guidance literature:

In tetrahydrofuran; under Ar atm., Co salt (1.05 equiv.) and C23H17F6N3 stirred in THF for 24 h; ppt. filtered off, washed (cold THF), dried under reduced pressure; elem. anal.;

DOI:10.1016/j.molcata.2011.03.015

upstream raw materials:

2,6-Diacetylpyridine

2-(trifluoromethyl)benzenamine

N?sulfinyl?2?trifluoromethylaniline

Downstream raw materials:

CoBr₂(NC₅H₃(CCH₃NC₆H₂(CF₃)H₂)2)

FeBr₂(NC₅H₃(CCH₃NC₆H₂(CF₃)H₂)2)

2,6-bis[1-(2-trifluoromethylphenylimino)ethyl]pyridine cobalt(II) chloride