5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine

Base Information

• Chemical Name: 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine
• CAS No.: 132062-67-0
• Molecular Formula: C₃₉H₃₉N₅O₁₀S₂
• Molecular Weight: 801.898

Synonyms:5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine

Chemical Property of 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine

There total 1 articles about 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-[9-((R)-2-Hydroxy-1-{(S)-1-hydroxymethyl-2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethoxy}-ethyl)-9H-purin-6-yl]-benzamide (98815-82-8) + methanesulfonyl chloride (124-63-0) → 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N6-benzoyl-2',3'-secoadenosine (132062-67-0)

Guidance literature:

With pyridine; for 1.5h; Ambient temperature;

Reference yield: 91.0%

5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N6-benzoyl-2',3'-secoadenosine (132062-67-0) + methylamine (74-89-5) → 9-(R)-<6-(R)-(monomethoxytrityl)oxymethyl-N-methyl-1,4-morpholin-2-yl>adenine (132062-75-0)

Guidance literature:

In 1,4-dioxane; water; at 60 ℃; for 48h;

Reference yield: 80.0%

5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N6-benzoyl-2',3'-secoadenosine (132062-67-0) → 9-(R)-<6-(R)-(monomethoxytrityl)oxymethyl-1-oxa-4-thiacyclohexan-2-yl>adenine (132062-68-1)

Guidance literature:

With sodium sulfide; In 1,4-dioxane; water; at 90 ℃; for 6h;

upstream raw materials:

N-[9-((R)-2-Hydroxy-1-{(S)-1-hydroxymethyl-2-[(4-methoxy-phenyl)-diphenyl-methoxy]-ethoxy}-ethyl)-9H-purin-6-yl]-benzamide

methanesulfonyl chloride

Downstream raw materials:

9-(R)-<6-(R)-(monomethoxytrityl)oxymethyl-1-oxa-4-thiacyclohexan-2-yl>adenine

9-(R)-<6-(R)-(monomethoxytrityl)oxymethyl-N-methyl-1,4-morpholin-2-yl>adenine

9-(R)-<6-(R)-(monomethoxytrityl)oxymethyl-N-benzyl-1,4-morpholin-2-yl>adenine

9-(R)-<6-(R)-hydroxymethyl-1-oxa-4-thiacyclohexan-2-yl>hypoxanthine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 132062-67-0 5'-O-monomethoxytrityl-2',3'-di-O-methanesulfonyl-N⁶-benzoyl-2',3'-secoadenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send