C₁₆H₁₁FN₂O

Base Information

• Chemical Name: C₁₆H₁₁FN₂O
• CAS No.: 1152934-95-6
• Molecular Formula: C₁₆H₁₁FN₂O
• Molecular Weight: 266.275
• Mol file: 1152934-95-6.mol

Synonyms:C₁₆H₁₁FN₂O

Chemical Property of C₁₆H₁₁FN₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₁FN₂O

There total 4 articles about C₁₆H₁₁FN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H13FN2 (94123-57-6) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → C16H11FN2O (1152934-95-6)

Guidance literature:

N,N-dimethyl-formamide; With trichlorophosphate; at 0 - 5 ℃; for 0.5h;

C₁₄H₁₃FN₂; In N,N-dimethyl-formamide; at 50 ℃; for 3h;

DOI:10.1016/j.ejmech.2011.12.011

Reference yield:

2'-Fluoroacetophenone (445-27-2) → C16H11FN2O (1152934-95-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid; sodium hydroxide / ethanol / 1 h / Reflux

2.1: trichlorophosphate / 0.5 h / 0 - 5 °C

2.2: 3 h / 50 °C

With acetic acid; sodium hydroxide; trichlorophosphate; In ethanol;

DOI:10.1016/j.ejmech.2011.12.011

Reference yield:

phenylhydrazine (100-63-0) → C16H11FN2O (1152934-95-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic acid; sodium hydroxide / ethanol / 1 h / Reflux

2.1: trichlorophosphate / 0.5 h / 0 - 5 °C

2.2: 3 h / 50 °C

With acetic acid; sodium hydroxide; trichlorophosphate; In ethanol;

DOI:10.1016/j.ejmech.2011.12.011

upstream raw materials:

C₁₄H₁₃FN₂

N,N-dimethyl-formamide

2'-Fluoroacetophenone

phenylhydrazine

Downstream raw materials:

C₂₈H₂₀FN₃O₃S₂