1,2-bis[2-(carboxy methoxy)phenoxy]ethane

Base Information

• Chemical Name: 1,2-bis[2-(carboxy methoxy)phenoxy]ethane
• CAS No.: 69448-36-8
• Molecular Formula: C₁₈H₁₈O₈
• Molecular Weight: 362.336
• Mol file: 69448-36-8.mol

Synonyms:1,2-bis[2-(carboxy methoxy)phenoxy]ethane

Chemical Property of 1,2-bis[2-(carboxy methoxy)phenoxy]ethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1,2-bis[2-(carboxy methoxy)phenoxy]ethane

There total 3 articles about 1,2-bis[2-(carboxy methoxy)phenoxy]ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1,2-bis(o-hydroxyphenoxy)ethane (20115-81-5) + ethyl bromoacetate (105-36-2) → 1,2-bis[2-(carboxy methoxy)phenoxy]ethane (69448-36-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 16h; steam bath;

Reference yield: 38.0%

1,2-bis(o-hydroxyphenoxy)ethane (20115-81-5) + bromoacetic acid (79-08-3) → 1,2-bis[2-(carboxy methoxy)phenoxy]ethane (69448-36-8)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran;

DOI:10.1246/cl.1993.1487

Reference yield:

2,2'-(Ethylendioxy)diphenoldibenzylether (73961-19-0) → 1,2-bis[2-(carboxy methoxy)phenoxy]ethane (69448-36-8)

Guidance literature:

Multi-step reaction with 2 steps

1: HBr / aq. acetic acid / 18 h

2: 45 percent / K₂CO₃ / dimethylformamide / 16 h / steam bath

With hydrogen bromide; potassium carbonate; In acetic acid; N,N-dimethyl-formamide;

upstream raw materials:

1,2-bis(o-hydroxyphenoxy)ethane

bromoacetic acid

ethyl bromoacetate

2,2'-(Ethylendioxy)diphenoldibenzylether

Downstream raw materials:

1,2-bis<2-(2-methylsulfonyloxyethyloxy)phenoxy>ethane

1,2-bis(2-ethoxyphenol)ethane