20115-81-5

Basic information

• Product Name: 1,2-BIS(2-HYDROXYPHENOXY)ETHANE
• Synonyms: 1,2-BIS(2-HYDROXYPHENOXY)ETHANE;2,2'-ETHYLENEDIOXYDIPHENOL;ETHYLENE GLYCOL BIS(2-HYDROXYPHENYL) ETHER;1,2-Bis(2-hydroxyphenoxy)ethane Ethylene Glycol Bis(2-hydroxyphenyl) Ether;2-[2-(2-hydroxyphenoxy)ethoxy]phenol
• CAS NO: 20115-81-5
• Molecular Formula: C₁₄H₁₄O₄
• Molecular Weight: 246.26
• Mol File: 20115-81-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-BIS(2-HYDROXYPHENOXY)ETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-BIS(2-HYDROXYPHENOXY)ETHANE(20115-81-5)
• EPA Substance Registry System: 1,2-BIS(2-HYDROXYPHENOXY)ETHANE(20115-81-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 20115-81-5(Hazardous Substances Data)

Usage

Uses

Used in Plastics and Epoxy Resin Industry:
1,2-Bis(2-hydroxyphenoxy)ethane is used as a key component in the production of various types of plastics and epoxy resins for its ability to provide strength, flexibility, and heat resistance to the final products. This makes it suitable for a wide range of applications, including the manufacturing of consumer goods such as water bottles, food containers, and dental sealants.
Used in Consumer Product Manufacturing:
1,2-Bis(2-hydroxyphenoxy)ethane is used as a critical ingredient in the creation of consumer products due to its versatility and the durability it imparts to the materials. Its presence in these products, however, has raised health concerns, leading to increased scrutiny and regulatory measures to ensure consumer safety.

Upstream product

• 120-80-9 benzene-1,2-diol 
• 21645-25-0 phenol 2-[(tetrahydro-2H-pyran-2yl)oxy] 
• 553-45-7 1,2-bis(2’-methoxyphenoxy)ethane 
• 6272-38-4 O-benzylcatechol 
• 107-21-1 ethylene glycol 
• 73961-19-0 2,2'-(Ethylendioxy)diphenoldibenzylether 
• 106-93-4 ethylene dibromide 

Downstream Products

• 65659-47-4 2-<2-<2-(2-hydroxyphenoxy)ethoxy>phenoxy>ethanol 
• 97546-26-4 2-(2-{2-[2-(1-Carboxy-ethoxy)-phenoxy]-ethoxy}-phenoxy)-propionic acid 
• 14262-60-3 dibenzo-15-crown-5 
• 14262-61-4 6,7,9,10,12,13,20,21-octahydrodibenzo[b,h][1,4,7,10,13,16]hexaoxacyclooctadecine 
• 220150-47-0 1,2-di[2-(2'-carboxydecyloxy)phenoxy]ethane 
• 86045-02-5 2,2'-<1,2-Ethandiylbis(oxy-2,1-phenylenoxy-2,1-ethandiyloxy)>diphenol 
• 69448-36-8 1,2-bis[2-(carboxy methoxy)phenoxy]ethane 
• 86044-99-7 2,2'-<1,2-Ethandiylbis(oxy-2,1-phenylenoxy-2,1-ethandiyloxy)>diphenol-dibenzylether 
• 82264-96-8 2,2'-<1,2-Ethandiyloxybis(oxy-2,1-phenylenoxy)>bisethanol-dibenzylether 
• 97546-23-1 1,2-bis-<-(1-carboxydecyloxy)phenoxy>ethane 
• 87117-67-7 2,2'-(1,2-Ethandiyloxy)bisphenol-didodecylether 
• 97546-27-5 2-(2-{2-[2-(1-Carboxy-1-methyl-ethoxy)-phenoxy]-ethoxy}-phenoxy)-2-methyl-propionic acid 
• 133560-78-8 <2,5>-dibenzo-21-crown-7 
• 211870-42-7 1,2-bis<2-(2-methylsulfonyloxyethyloxy)phenoxy>ethane 

Relevant articles and documents

Highly efficient synthesis of tetra benzo spiro bis-crown ether

Novel spiro bis-crown ethers derivatives with four benzo units connected via one carbon bridges have been prepared. These compounds represent well preorganized cavities with interesting complexation abilities towards cations. These macrocyclic were prepared by a four-step via template method by utilizing simple precursors catechol, oliethylen glycol and penta erythritol tetra bromide in good yield. Additionally, cesium carbonate could be used as an excellent base for these reactions.

Polybenzocrown ethers: Synthesis by cesium-assisted cyclization and solid-state structures

A series of large-ring polybenzocrown ethers is prepared by cesium-assisted cyclizations. Reactions of diphenols/bisphenols, dimesylates of oligoethylene glycols and cesium carbonate in MeCN produce the large-ring polybenzocrown ethers in high yields. To gain further insight into the structures of these compounds, solid-state structures of three large-ring crown ethers are obtained by X-ray diffraction.

Structural features of a sulfur-containing group 4 metalla[11]-crown-4 derivative

Treatment of the ligand system (o-C6H4OH)-S-CH 2-CH2-S-(o-C6H4-OH) (2a) with TiCl4 gave the metalla-crown ether derivative [(-S-CH 2-CH2-S-)(o-C6

Macroring-Neutral Molecule Complexation. Synthesis of Biconcave Pyridino Hosts, Complex Formation, and X-ray Crystal Structures of Two Inclusion Compounds

A series of pyridino macrocycles 1-3(a-e) incorporating rigid bi- and triaryl ether segments in different ring positions have been synthesized.The effect of incorporation of these building blocks into a given macroring framework on the host properties for

The Stereochemistry of Crown Ethers II -- 1H and 13C NMR Structural Study in Solution

The 1H and 13C NMR spectra of a series of structurally related crown ethers have been recorded, and the signals assigned by means of 1H/13C heteronuclear correlated and 1H/1H homonuclear NOE difference spectroscopy.The NMR parameters so extracted have been used to discuss the preferred, rapidly interconverting solution conformations of the studied species.The high-field shifts in the 13C NMR spectra, within the so-called γ-fragments, and also the 1H/1H homonuclear NOEs, are particularly informative in this respect.The T1 relaxation times of the 13C atoms show segmental motions within the ether segments and suggest different intramolecular flexibilities for the studied compounds.KEY WORDS 1H/13C NMR 2D and 1D NOE difference spectroscopy Crown ethers Conformations in solution Intramolecular flexibility.

Calcium ionophores as cardiac stimulants. I. Diacids derived from dibenzo crown ethers

A series of calcium chelating agents has been prepared based on carboxylic derivatives of open chain 18-Crown-6 analogues. Most of these are efficient calcium binding agents, many form lipophilic calcium complexes, and some of these are capable of releasing Ca2+ from liposomes by ionophore action. The best of these is 1,2-bis-[2-(1-carboxydecyloxy)phenoxy]ethane. This compound is cardiotonic in vitro but in the dog vasoconstriction it is the predominant biological effect.

Complexes Between Neutral Molecules, VII. Crown Ethers as Host Compounds for Organic Guest Molecules

Neutral, stoichiometric crystalline complexes of dibenzopyridino crown ether 2 with other crown ethers such as crown-4 and with CH-acidic molecules such as acetonitrile, nitromethane, dimethyl sulfoxide as well as with formamide, dimethylformamide, di