1-(Trifluoromethyl)cyclohex-2-en-1-ol

Base Information

Chemical Name:1-(Trifluoromethyl)cyclohex-2-en-1-ol
CAS No.:118143-28-5
Molecular Formula:C7H9 F3 O
Molecular Weight:166.143
Hs Code.:2906199090
DSSTox Substance ID:DTXSID60446743
Nikkaji Number:J376.465F
Mol file:118143-28-5.mol

Synonyms:1-(trifluoromethyl)cyclohex-2-en-1-ol;118143-28-5;3-HYDROXY-3-(TRIFLUOROMETHYL)CYCLOHEXENE;2-Cyclohexen-1-ol,1-(trifluoromethyl)-;DTXSID60446743;DFFKUOBCTWPVOA-UHFFFAOYSA-N;1-(trifluoromethyl)cyclohex-2-enol;AKOS006287779;1-(Trifluoromethyl)-2-cyclohexen-1-ol

Suppliers and Price of 1-(Trifluoromethyl)cyclohex-2-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-HYDROXY-3-(TRIFLUOROMETHYL)CYCLOHEXENE 95.00%
5G
$ 1262.48

Total 5 raw suppliers

Chemical Property of 1-(Trifluoromethyl)cyclohex-2-en-1-ol

Chemical Property:

PSA：20.23000
LogP:2.01990
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:166.06054939
Heavy Atom Count:11
Complexity:173

Purity/Quality:

98%min ^*data from raw suppliers

3-HYDROXY-3-(TRIFLUOROMETHYL)CYCLOHEXENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC=CC(C1)(C(F)(F)F)O

Technology Process of 1-(Trifluoromethyl)cyclohex-2-en-1-ol

There total 5 articles about 1-(Trifluoromethyl)cyclohex-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 930-68-7
cyclohexenone

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 118143-28-5
1-(trifluoromethyl)-2-cyclohexen-1-ol

Guidance literature:: With N-(EtOCH₂CH₂OCH₂)-N-methylmorpholinium bis(CF₃SO₂)amide; cesium fluoride; at 25 ℃; for 0.5h;
DOI:10.1039/b412480b

Reference yield: 92.0%

: 247912-53-4
Trimethyl-(1-trifluoromethyl-cyclohex-2-enyloxy)-silane

: 118143-28-5
1-(trifluoromethyl)-2-cyclohexen-1-ol

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/ol990844r

Reference yield:

: 930-68-7
cyclohexenone

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 585-36-4
3-(trifluoromethyl)cyclohexanone

: 118143-28-5
1-(trifluoromethyl)-2-cyclohexen-1-ol

Guidance literature:: With hydrogenchloride; tetrabutyl ammonium fluoride; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1) THF, 0 deg C - rt;
DOI:10.1021/jo00003a017