2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid

Base Information

• Chemical Name: 2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid
• CAS No.: 891790-05-9
• Molecular Formula: C₁₅H₁₂BrClN₂O₃
• Molecular Weight: 383.629
• Mol file: 891790-05-9.mol

Synonyms:2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid

Chemical Property of 2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid

There total 1 articles about 2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-2-(2-bromophenyl)acetic acid (254762-66-8,339274-34-9) + p-chlorphenylisocyanate (104-12-1) → 2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid (891790-05-9)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid (891790-05-9) + 1-(1-methyl-piperidin-4-yl)-piperazine (23995-88-2) → C25H31BrClN5O2

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

Reference yield:

2-(2-bromophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid (891790-05-9) + 4-amino-1-isopropylpiperidine (127285-08-9) → N-(1-isopropylpiperidin-4-yl)-2-(2-bromophenyl)-2-((4-chlorophenylamino)carbonylamino)-acetamide

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃;

upstream raw materials:

2-amino-2-(2-bromophenyl)acetic acid

p-chlorphenylisocyanate