N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide

Base Information

Chemical Name:N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide
CAS No.:386297-97-8
Molecular Formula:C₂₁H₂₆N₄O₂
Molecular Weight:366.463
Hs Code.:
UNII:PQF723MLIV
ChEMBL ID:CHEMBL480041
DSSTox Substance ID:DTXSID001126663
Nikkaji Number:J2.310.830E
Wikidata:Q5205912
Wikipedia:DPA-713

Synonyms:DPA-713;N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamide

Suppliers and Price of N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:366.20557608
Heavy Atom Count:27
Complexity:491

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN(CC)C(=O)CC1=C2N=C(C=C(N2N=C1C3=CC=C(C=C3)OC)C)C

Technology Process of N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide

There total 8 articles about N,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 123-54-6,81235-32-7
acetylacetone

: 386298-19-7
2-[3-amino-5-(4'-methoxyphenyl)-1H-pyrazol-4-yl]-N,N-diethylacetamide

: 386297-97-8
2-[2-(4'-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]-N,N-diethylacetamide

Guidance literature:: In ethanol; for 12h; Heating;
DOI:10.1016/j.bmc.2005.06.030

Reference yield: 85.0%

: 2-(5-amino-3-(4-methoxyphenyl)-1H-pyrazol-4-yl)-N,N-diethylacetamide

: 123-54-6,81235-32-7
acetylacetone

: 386297-97-8
2-[2-(4'-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]-N,N-diethylacetamide

Guidance literature:: In ethanol; at 60 ℃; for 20h; Microwave irradiation;
DOI:10.1021/acs.biomac.0c01033

Reference yield:

: 3672-47-7
3-oxo-3-(4'-methoxyphenyl)propanenitrile

: 386297-97-8
2-[2-(4'-methoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl]-N,N-diethylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / sodium iodide; NaOH / ethanol; H₂O / 7 h / 20 °C

2: 68 percent / hydrazine hydrate; acetic acid / ethanol / 4 h / Heating

3: 93 percent / ethanol / 12 h / Heating

With sodium hydroxide; hydrazine hydrate; acetic acid; sodium iodide; In ethanol; water;
DOI:10.1016/j.bmc.2005.06.030