N₁,N₁-diphenyl-1,3-phenylenediamine

Base Information

• Chemical Name: N₁,N₁-diphenyl-1,3-phenylenediamine
• CAS No.: 116724-06-2
• Molecular Formula: C₁₈H₁₆N₂
• Molecular Weight: 260.338
• Mol file: 116724-06-2.mol

Synonyms:N₁,N₁-diphenyl-1,3-phenylenediamine

Chemical Property of N₁,N₁-diphenyl-1,3-phenylenediamine

Chemical Property:

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁,N₁-diphenyl-1,3-phenylenediamine

There total 10 articles about N₁,N₁-diphenyl-1,3-phenylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-(N,N-diphenylamino)nitrobenzene (100148-35-4) → N1,N1-diphenyl-1,3-phenylenediamine (116724-06-2)

Guidance literature:

With iron; ammonium chloride; In ethanol; water; for 4h; Reflux;

Reference yield:

C31H24N2 → N1,N1-diphenyl-1,3-phenylenediamine (116724-06-2)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 22 ℃; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.8b00646

Reference yield:

diphenylamine (122-39-4) → N1,N1-diphenyl-1,3-phenylenediamine (116724-06-2)

Guidance literature:

Multi-step reaction with 2 steps

1: CyJohnPhos; sodium t-butanolate / palladium diacetate / toluene / 18 h / Reflux

2: hydrogen / palladium 10% on activated carbon / ethyl acetate / 1 h / 2068.65 Torr

With hydrogen; sodium t-butanolate; CyJohnPhos; palladium 10% on activated carbon; palladium diacetate; In ethyl acetate; toluene;

upstream raw materials:

3-(N,N-diphenylamino)nitrobenzene

ethanol

acetic acid

iodobenzene

Downstream raw materials:

N₃-(3-(diphenylamino)phenyl)-N₂-methylpyridine-2,3-diamine

Refernces

• 1、 -. "FLUORESCENT DYE AGENT AND CARBOSTYRIL COMPOUND". Paragraph 0153; 0154. . Retrieved 2019/04/03.
• 2、 Mikhailine, Alexandre A.,Grasa Mannino, Gabriela A.,Colacot, Thomas J.. "Catalyst-Directed Chemoselective Double Amination of Bromo-chloro(hetero)arenes: A Synthetic Route toward Advanced Amino-aniline Intermediates". . p. 2301 - 2305. Retrieved 2018/04/30.