TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER

Base Information

• Chemical Name: TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER
• CAS No.: 114413-26-2
• Molecular Formula: C₉H₂₀O₂Si
• Molecular Weight: 188.342
• Mol file: 114413-26-2.mol

Synonyms:TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER

Chemical Property of TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER

Chemical Property:

• Refractive Index: n20/D 1.531(lit.)
• Boiling Point: 195-197 °C(lit.)
• Flash Point: 158 °F
• PSA: 21.76000
• Density: 0.901 g/mL at 25 °C(lit.)
• LogP: 1.55550

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER

There total 20 articles about TERT-BUTYLMETHYLSILYL GLYCIDYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyldimethylsilyl chloride (18162-48-6) + (R)-oxiranemethanol (57044-25-4) → tert-butyldimethylsilyl (S)-glycidyl ether (78906-15-7,114413-26-2,124150-87-4,123237-62-7)

Guidance literature:

With 1H-imidazole; triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/chem.200802681

Reference yield: 95.0%

oxiranyl-methanol (556-52-5) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyldimethylsilyl glycidyl ether (114413-26-2,123237-62-7,124150-87-4,78906-15-7)

Guidance literature:

With 1H-imidazole; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol401787n

Reference yield: 73.0%

Allyloxy-tert-butyl-dimethyl-silane (85807-85-8) → tert-butyldimethylsilyl glycidyl ether (114413-26-2,123237-62-7,124150-87-4,78906-15-7)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(01)86217-7

upstream raw materials:

Allyloxy-tert-butyl-dimethyl-silane

oxiranyl-methanol

tert-butyldimethylsilyl chloride

1H-imidazole

Downstream raw materials:

1-((tert-butyldimethylsilyl)oxy)-3-phenylpropan-2-ol

1-(tert-butyl-dimethylsilyloxy)-4-phenylbutan-2-ol

(2S,4R)-2-Benzyl-5-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

(S)-1-(tert-Butyl-dimethyl-silanyloxy)-7-(4-methoxy-benzyloxy)-6-(tetrahydro-pyran-2-yloxy)-hept-4-yn-2-ol