tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate

Base Information

• Chemical Name: tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate
• CAS No.: 250213-47-9
• Molecular Formula: C₁₇H₂₅N₃O₃
• Molecular Weight: 319.404
• Mol file: 250213-47-9.mol

Synonyms:tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate

Chemical Property of tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate

There total 1 articles about tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

tert-butyl 2-azidoacetate (6367-36-8) + 4-tert-Butylbenzaldehyde (939-97-9) → tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate (250213-47-9)

Guidance literature:

With sodium isopropylate; In isopropyl alcohol; at -30 ℃; for 4h;

DOI:10.1248/cpb.47.1227

Reference yield: 81.0%

tert-butyl 2-azido-3-(tert-butylphenyl)-3-hydroxypropionate (250213-47-9) → tert-butyl 2-azido-4'-tert-butylcinnamate (250213-52-6)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In dichloromethane; at -40 ℃; for 0.166667h;

DOI:10.1248/cpb.47.1227

upstream raw materials:

tert-butyl 2-azidoacetate

4-tert-Butylbenzaldehyde

Downstream raw materials:

tert-butyl 2-azido-4'-tert-butylcinnamate