N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide
CAS No.:1125632-69-0
Molecular Formula:C₁₄H₈ClF₃N₄O₂S
Molecular Weight:388.757
Hs Code.:

Synonyms:N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Suppliers and Price of N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

There total 6 articles about N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1125632-67-8
N-{5-[(5-aminopyridin-2-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

: 333-20-0
potassium thioacyanate

: 1125632-69-0
N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Guidance literature:: N-{5-[(5-aminopyridin-2-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide; potassium thioacyanate; With bromine; acetic acid; at 20 ℃; for 16h; Cooling with ice;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 1125632-63-4
2-chloro-5-[(5-nitropyridin-2-yl)oxy]aniline

: 1125632-69-0
N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran / 1 h / 20 °C

2: acetic acid; iron / 3 h / 60 °C

3: bromine; acetic acid / 16 h / 20 °C / Cooling with ice

With bromine; iron; acetic acid; In tetrahydrofuran;

Reference yield:

: 1125632-65-6
N-{2-chloro-5-[(5-nitropyridin-2-yl)oxy]phenyl}-2,2,2-trifluoroacetamide

: 1125632-69-0
N-{5-[(2-amino[1,3]-thiazolo[5,4-b]pyridin-5-yl)oxy]-2-chlorophenyl}-2,2,2-trifluoroacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; iron / 3 h / 60 °C

2: bromine; acetic acid / 16 h / 20 °C / Cooling with ice

With bromine; iron; acetic acid;